Giants vs. Pirates Prediction: San Francisco Predicted to Win Tuesday's MLB Matchup [8/5/2025]

The Pittsburgh Pirates and San Francisco Giants will lock horns in MLB action at PNC Park on Tuesday, starting at 6:40PM ET.

The Pirates will start Mike Burrows (1-3, 3.88 ERA), while the Giants will counter with Logan Webb (9-8, 3.31 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) projects the Giants as the most likely winner of today's game.

For a closer look at Tuesday's matchup, including best bets and picks, visit our interactive Giants vs. Pirates predictions page.

Pirates vs. Giants Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Tuesday's MLB game between the Giants and Pirates 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Giants a 54% chance of beating the Pirates.

According to our model, the Pirates (+1.5) have a 59% chance of covering the run line, while the over/under total of 7.5 runs has a 51% chance of staying under.

Giants vs. Pirates Odds [8/5/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Giants	Pirates
Run Line	-1.5 (+126)	+1.5 (-144)
Moneyline	-144	+123
Total	o7.5 (+101)	u7.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Giants vs. Pirates Picks and Best Bets

Our model's strongest edge in today's Giants vs. Pirates matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Giants vs. Pirates Game-Day Updates and Essential Details

Tuesday's MLB game between the Pirates and Giants at PNC Park is scheduled to commence at 6:40PM ET.

• Who: San Francisco Giants vs. Pittsburgh Pirates
• Date: Tuesday, August 5, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's full preview of Tuesday's Giants vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Giants vs. Pirates picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Giants, with a 54% win probability, will likely beat the Pirates on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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