Giants vs. Pirates Prediction: San Francisco Predicted to Win Monday's MLB Matchup [8/4/2025]

The Pittsburgh Pirates and San Francisco Giants will meet in MLB action at PNC Park on Monday, starting at 6:40PM ET.

The Pirates will start Johan Oviedo (0-0, 0.00 ERA), while the Giants have opted for Justin Verlander (1-8, 4.53 ERA).

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Giants as the most likely winner of today's game.

For further insights into Monday's matchup, including best bets and picks, visit our interactive Giants vs. Pirates predictions page.

Pirates vs. Giants Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the result of Monday's MLB game between the Giants and Pirates 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Giants a 52% chance of beating the Pirates.

According to our model, the Pirates (+1.5) have a 61% chance of covering the run line, while the over/under total of 8.5 runs has a 52% chance of staying under.

Giants vs. Pirates Odds [8/4/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Giants	Pirates
Run Line	-1.5 (+130)	+1.5 (-152)
Moneyline	-127	+110
Total	o8.5 (-104)	u8.5 (-115)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Giants vs. Pirates Picks and Best Bets

Our model's strongest edge in today's Giants vs. Pirates matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Giants vs. Pirates Game-Day Updates and Essential Details

Monday's MLB game between the Pirates and Giants at PNC Park is scheduled to begin at 6:40PM ET.

• Who: San Francisco Giants vs. Pittsburgh Pirates
• Date: Monday, August 4, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's in-depth preview of Monday's Giants vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Giants vs. Pirates picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Giants, with a 52% win probability, will likely beat the Pirates on Monday.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.