Giants vs. Twins Prediction: Minnesota Predicted to Win Sunday's MLB Matchup [5/11/2025]

The Minnesota Twins will take on the San Francisco Giants in MLB action at Target Field on Sunday, commencing at 2:10PM ET.

The Twins will send Pablo López (3-2, 2.18 ERA) to the mound, while the Giants are going with Landen Roupp (2-3, 4.89 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Twins as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's San Francisco-Minnesota game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Twins with a win probability of 60%, while the Giants have 40%."

For a closer look at Sunday's matchup, including best bets and picks, visit our interactive Giants vs. Twins predictions page.

Twins vs. Giants Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data analysis, we have simulated the result of Sunday's MLB game between the Giants and Twins 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Twins a 60% chance of defeating the Giants.

According to our model, the Giants (+1.5) have a 60% chance of covering the run line, while the over/under total of 8.5 runs has a 53% chance of staying under.

Giants vs. Twins Odds [5/11/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Giants	Twins
Run Line	+1.5 (-154)	-1.5 (+140)
Moneyline	+138	-160
Total	o8.5 (-102)	u8.5 (-115)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Giants vs. Twins Picks and Best Bets

Our model's strongest edge in today's Giants vs. Twins matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Giants vs. Twins Game-Day Updates and Essential Details

Sunday's MLB action between the Twins and Giants at Target Field is scheduled to commence at 2:10PM ET.

• Who: San Francisco Giants vs. Minnesota Twins
• Date: Sunday, May 11, 2025
• Time: 2:10PM ET/11:10AM PT
• Venue: Target Field

Dimers.com's comprehensive preview of Sunday's Giants vs. Twins matchup includes our prediction, picks and the latest betting odds.

Before making any San Francisco vs. Minnesota picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
• Understand where sports odds come from and how they're applied to baseball matchups
• Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
• Stay informed with where online sports betting is currently legal and which betting sites are safest to use
• Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on

Conclusion

We predict the Twins, with a 60% win probability, will likely beat the Giants on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Twins insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay up-to-date with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the most accurate predictions for the World Series, American League, National League and each division.