Giants vs. Dodgers prediction: Cy Young candidate Robbie Ray takes on Dodgers tonight [9/19/2025]

The Los Angeles Dodgers and San Francisco Giants will lock horns in MLB action at Dodger Stadium on Friday, starting at 10:10PM ET.

Clayton Kershaw (10-2, 3.53 ERA) will be on the bump for the Dodgers, up against Cy Young hopeful Robbie Ray (11-7, 3.50 ERA) for the Giants.

Based on updated simulations, Dimers' advanced MLB model predicts the Dodgers as the most likely winner of today's game.

For a closer look at Friday's matchup, including best bets and picks, visit our interactive Giants vs. Dodgers predictions page.

Dodgers vs. Giants prediction: Who will win, cover the run line?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Friday's MLB matchup between the Giants and Dodgers 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Dodgers a 63% chance of beating the Giants.

According to our model, the Giants (+1.5) have a 57% chance of covering the run line, while the 9-run over/under has a 51% chance of going over.

Giants vs. Dodgers odds [9/19/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Giants	Dodgers
Run Line	+1.5 (-133)	-1.5 (+115)
Moneyline	+160	-184
Total	o9 (+100)	u9 (-111)

All odds are correct at the time of publication and are subject to change.

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Giants vs. Dodgers picks and best bets

Our model's strongest edge in today's Giants vs. Dodgers matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

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Giants vs. Dodgers game-day updates and essential details

Friday's MLB action between the Dodgers and Giants at Dodger Stadium is scheduled to start at 10:10PM ET.

• Who: San Francisco Giants vs. Los Angeles Dodgers
• Date: Friday, September 19, 2025
• Time: 10:10PM ET/7:10PM PT
• Venue: Dodger Stadium

Dimers' in-depth preview of Friday's Giants vs. Dodgers matchup includes our prediction, picks and the latest betting odds.

Before making any Giants vs. Dodgers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Dodgers, with a 63% win probability, will likely beat the Giants on Friday.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Dodgers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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