Giants vs. Rockies prediction: Why San Francisco is favored to win Labor Day MLB matchup [9/1/2025]

MLB action continues on Monday at 4:10PM ET as the San Francisco Giants lock horns with the Colorado Rockies at Coors Field.

Chase Dollander (2-11, 6.54 ERA) will get the ball for the Rockies, up against Kai-Wei Teng (1-3, 8.78 ERA) for the Giants.

Based on updated simulations, Dimers' proven MLB model predicts the Giants as the most likely winner of today's game.

For a closer look at Monday's matchup, including best bets and picks, visit our interactive Giants vs. Rockies predictions page.

Rockies vs. Giants prediction: Who will win, cover the run line?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Monday's MLB game between the Giants and Rockies 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Giants a 54% chance of defeating the Rockies.

According to our model, the Rockies (+1.5) have a 56% chance of covering the run line, while the over/under total of 11.5 runs has a 55% chance of staying under.

Giants vs. Rockies odds [9/1/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Giants	Rockies
Run Line	-1.5 (+105)	+1.5 (-115)
Moneyline	-140	+123
Total	o11.5 (-102)	u11.5 (-107)

All odds are correct at the time of publication and are subject to change.

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Giants vs. Rockies picks and best bets

Our model's biggest edge in today's Giants vs. Rockies matchup is on the run line.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets today

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Giants vs. Rockies game-day updates and essential details

Monday's MLB matchup between the Rockies and Giants at Coors Field is scheduled to begin at 4:10PM ET.

• Who: San Francisco Giants vs. Colorado Rockies
• Date: Monday, September 1, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: Coors Field

Dimers.com's full preview of Monday's Giants vs. Rockies matchup includes our prediction, picks and the latest betting odds.

Before making any Giants vs. Rockies picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Giants, with a 54% win probability, will likely beat the Rockies on Monday.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Rockies insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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