Giants vs. Diamondbacks Prediction: Arizona Predicted to Win Wednesday's MLB Matchup [7/2/2025]

The Arizona Diamondbacks will square off with the San Francisco Giants in MLB action at Chase Field on Wednesday, commencing at 9:40PM ET.

Merrill Kelly (7-4, 3.49 ERA) will start on the mound for the Diamondbacks, while the Giants will counter with Landen Roupp (6-5, 3.43 ERA).

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Diamondbacks as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Giants-Diamondbacks game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Diamondbacks' chance of winning at 57%, with the Giants at 43%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Giants vs. Diamondbacks predictions page.

Diamondbacks vs. Giants Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Wednesday's MLB game between the Giants and Diamondbacks 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Diamondbacks a 57% chance of defeating the Giants.

According to our model, the Giants (+1.5) have a 63% chance of covering the run line, while the 8.5-run over/under has an equal 50-50 chance of hitting.

Giants vs. Diamondbacks Odds [7/2/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Giants	Diamondbacks
Run Line	+1.5 (-165)	-1.5 (+152)
Moneyline	+125	-142
Total	o8.5 (-110)	u8.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Giants vs. Diamondbacks Picks and Best Bets

Our model's biggest edge in today's Giants vs. Diamondbacks matchup is on the over/under.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Giants vs. Diamondbacks Game-Day Updates and Essential Details

Wednesday's MLB game between the Diamondbacks and Giants at Chase Field is scheduled to commence at 9:40PM ET.

• Who: San Francisco Giants vs. Arizona Diamondbacks
• Date: Wednesday, July 2, 2025
• Time: 9:40PM ET/6:40PM PT
• Venue: Chase Field

Dimers.com's comprehensive preview of Wednesday's Giants vs. Diamondbacks matchup includes our prediction, picks and the latest betting odds.

Before making any Giants vs. Diamondbacks picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Diamondbacks, with a 57% win probability, will likely beat the Giants on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Diamondbacks insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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