Giants vs. Diamondbacks Prediction: San Francisco Predicted to Win Monday's MLB Matchup [6/30/2025]

The Arizona Diamondbacks will square off with the San Francisco Giants in MLB action at Chase Field on Monday, starting at 9:40PM ET.

The Diamondbacks will send Ryne Nelson (4-2, 3.71 ERA) to the mound, while the Giants will counter with Logan Webb (7-5, 2.52 ERA).

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Giants as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's Giants-Diamondbacks game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Giants are likely to win, with a probability of 55%, compared to the Diamondbacks' 45%."

For a closer look at Monday's matchup, including best bets and picks, visit our interactive Giants vs. Diamondbacks predictions page.

Diamondbacks vs. Giants Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the result of Monday's MLB matchup between the Giants and Diamondbacks 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Giants a 55% chance of beating the Diamondbacks.

According to our model, the Diamondbacks (+1.5) have a 58% chance of covering the run line, while the over/under total of 8 runs has a 53% chance of going over.

Giants vs. Diamondbacks Odds [6/30/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Giants	Diamondbacks
Run Line	-1.5 (+115)	+1.5 (-132)
Moneyline	-148	+126
Total	o8 (-112)	u8 (-105)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Giants vs. Diamondbacks Picks and Best Bets

Our model's biggest edge in today's Giants vs. Diamondbacks matchup is on the over/under.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Giants vs. Diamondbacks Game-Day Updates and Essential Details

Monday's MLB matchup between the Diamondbacks and Giants at Chase Field is scheduled to commence at 9:40PM ET.

• Who: San Francisco Giants vs. Arizona Diamondbacks
• Date: Monday, June 30, 2025
• Time: 9:40PM ET/6:40PM PT
• Venue: Chase Field

Dimers.com's comprehensive preview of Monday's Giants vs. Diamondbacks matchup includes our prediction, picks and the latest betting odds.

Before making any Giants vs. Diamondbacks picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
• Understand where sports odds come from and how they're applied to baseball matchups
• Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
• Stay informed with where online sports betting is currently legal and which betting sites are safest to use
• Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on

Conclusion

We predict the Giants, with a 55% win probability, will likely beat the Diamondbacks on Monday.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Diamondbacks insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay up-to-date with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest probabilities for the World Series, American League, National League and each division.