Padres vs. Nationals Prediction: San Diego Predicted to Win Saturday's MLB Matchup [7/19/2025]

The Washington Nationals will take on the San Diego Padres in MLB action at Nationals Park on Saturday, commencing at 6:45PM ET.

The Nationals will send Mitchell Parker (5-10, 5.12 ERA) to the mound, up against Yu Darvish (0-1, 6.48 ERA) for the Padres.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Padres as the most likely winner of today's game.

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Padres vs. Nationals predictions page.

Nationals vs. Padres Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the result of Saturday's MLB game between the Padres and Nationals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Padres a 53% chance of defeating the Nationals.

According to our model, the Nationals (+1.5) have a 60% chance of covering the run line, while the over/under total of 9 runs has a 51% chance of staying under.

Padres vs. Nationals Odds [7/19/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Padres	Nationals
Run Line	-1.5 (+120)	+1.5 (-142)
Moneyline	-134	+118
Total	o9 (-114)	u9 (-105)

All odds are correct at the time of publication and are subject to change.

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Padres vs. Nationals Picks and Best Bets

Our model's strongest edge in today's Padres vs. Nationals matchup is on the total.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Padres vs. Nationals Game-Day Updates and Essential Details

Saturday's MLB matchup between the Nationals and Padres at Nationals Park is scheduled to commence at 6:45PM ET.

• Who: San Diego Padres vs. Washington Nationals
• Date: Saturday, July 19, 2025
• Time: 6:45PM ET/3:45PM PT
• Venue: Nationals Park

Dimers.com's comprehensive preview of Saturday's Padres vs. Nationals matchup includes our prediction, picks and the latest betting odds.

Before making any Padres vs. Nationals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Padres, with a 53% win probability, will likely beat the Nationals on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Nationals insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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