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Padres vs. Blue Jays Prediction: San Diego Predicted to Win Tuesday's MLB Matchup [5/20/2025]

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Written by Jason Bevilacqua

Our expert prediction for Tuesday's San Diego Padres vs Toronto Blue Jays matchup.

San Diego Padres-Toronto Blue Jays Predictions and Game Preview.
Rogers Centre sets the stage for the MLB matchup between the San Diego Padres and Toronto Blue Jays this Tuesday.

MLB action continues on Tuesday at 7:07PM ET as the San Diego Padres square off with the Toronto Blue Jays at Rogers Centre.

The Blue Jays will have Chris Bassitt (3-2, 3.16 ERA) as their starting pitcher, while the Padres will counter with Dylan Cease (1-2, 4.60 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Padres as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's San Diego-Toronto game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Padres with a win probability of 52%, compared to 48% for the Blue Jays."

For a closer look at Tuesday's matchup, including best bets and picks, visit our interactive Padres vs. Blue Jays predictions page.

Blue Jays vs. Padres Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Tuesday's MLB matchup between the Padres and Blue Jays 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Padres a 52% chance of defeating the Blue Jays.

According to our model, the Blue Jays (+1.5) have a 62% chance of covering the run line, while the 7.5-run over/under has a 53% chance of going over.

 

Padres vs. Blue Jays Odds [5/20/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Padres Blue Jays
Run Line -1.5 (+155) +1.5 (-178)
Moneyline -108 -108
Total o7.5 (-114) u7.5 (-105)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Padres vs. Blue Jays Picks and Best Bets

Our model's biggest edge in today's Padres vs. Blue Jays matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Padres vs. Blue Jays Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Blue Jays and Padres at Rogers Centre is scheduled to commence at 7:07PM ET.

Dimers.com's full preview of Tuesday's Padres vs. Blue Jays matchup includes our prediction, picks and the latest betting odds.

Before making any San Diego vs. Toronto picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Padres, with a 52% win probability, will likely beat the Blue Jays on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Blue Jays insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest projections for the World Series, American League, National League and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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