Padres vs. Giants Prediction: San Francisco Predicted to Win Monday's MLB Matchup [8/11/2025]

The San Francisco Giants and San Diego Padres will meet in MLB action at Oracle Park on Monday, starting at 9:45PM ET.

The Giants will start Logan Webb (10-8, 3.24 ERA), while the Padres have opted for Yu Darvish (1-3, 6.51 ERA).

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Giants as the most likely winner of today's game.

For further insights into Monday's matchup, including best bets and picks, visit our interactive Padres vs. Giants predictions page.

Giants vs. Padres Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Monday's MLB game between the Padres and Giants 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Giants a 52% chance of beating the Padres.

According to our model, the Padres (+1.5) have a 66% chance of covering the run line, while the 7.5-run over/under has a 52% chance of going over.

Padres vs. Giants Odds [8/11/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Padres	Giants
Run Line	+1.5 (-190)	-1.5 (+164)
Moneyline	+111	-130
Total	o7.5 (-102)	u7.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Padres vs. Giants Picks and Best Bets

Our model's biggest edge in today's Padres vs. Giants matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Padres vs. Giants Game-Day Updates and Essential Details

Monday's MLB game between the Giants and Padres at Oracle Park is scheduled to begin at 9:45PM ET.

• Who: San Diego Padres vs. San Francisco Giants
• Date: Monday, August 11, 2025
• Time: 9:45PM ET/6:45PM PT
• Venue: Oracle Park

Dimers.com's in-depth preview of Monday's Padres vs. Giants matchup includes our prediction, picks and the latest betting odds.

Before making any Padres vs. Giants picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Giants, with a 52% win probability, will likely beat the Padres on Monday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Giants insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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