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Padres vs. Yankees Prediction: Yankees Predicted to Win Monday's MLB Matchup [5/5/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Our expert prediction for Monday's San Diego Padres vs New York Yankees matchup.
The New York Yankees will square off with the San Diego Padres in MLB action at Yankee Stadium on Monday, beginning at 7:05PM ET.
The Yankees will send Carlos Rodón (4-3, 3.43 ERA) to the mound, pitting him against Nick Pivetta (5-1, 1.78 ERA) for the Padres.
Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Yankees as the most likely winner of today's game.
"Our team has utilized the latest data to simulate Monday's San Diego-NY Yankees game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.
"Incorporating recent updates and thousands of additional inputs, our prediction shows the Yankees are likely to win, with a probability of 56%, compared to the Padres' 44%."
For expanded analysis of Monday's matchup, including best bets and picks, visit our interactive Padres vs. Yankees predictions page.
Yankees vs. Padres Prediction: Who Will Win, Cover the Run Line?
Using innovative machine learning and data, we have simulated the outcome of Monday's MLB game between the Padres and Yankees 10,000 times as part of our MLB predictions coverage.
Our famous predictive model currently gives the Yankees a 56% chance of beating the Padres.
According to our model, the Padres (+1.5) have a 62% chance of covering the run line, while the 8-run over/under has a 54% chance of staying under.
Padres vs. Yankees Odds [5/5/2025]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Padres | Yankees |
|---|---|---|
| Run Line | +1.5 (-160) | -1.5 (+140) |
| Moneyline | +136 | -154 |
| Total | o8 (-102) | u8 (-120) |
All odds are correct at the time of publication and are subject to change.
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Padres vs. Yankees Picks and Best Bets
Our model's strongest edge in today's Padres vs. Yankees matchup is on the moneyline.
Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Best Bets Video
Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.
Padres vs. Yankees Game-Day Updates and Essential Details
Monday's MLB game between the Yankees and Padres at Yankee Stadium is scheduled to begin at 7:05PM ET.
- Who: San Diego Padres vs. New York Yankees
- Date: Monday, May 5, 2025
- Time: 7:05PM ET/4:05PM PT
- Venue: Yankee Stadium
Dimers.com's comprehensive preview of Monday's Padres vs. Yankees matchup includes our prediction, picks and the latest betting odds.
Before making any San Diego vs. NY Yankees picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Key MLB Betting Guides and Insights
- Explore how MLB odds work and dive into MLB live betting strategies
- Understand where sports odds come from and how they're applied to baseball matchups
- Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
- Stay informed with where online sports betting is currently legal and which betting sites are safest to use
- Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on
Conclusion
We predict the Yankees, with a 56% win probability, will likely beat the Padres on Monday.
AI and automation have enhanced this article to quickly deliver accurate Padres vs. Yankees insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Stay informed with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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