Padres vs. Mets prediction: Mets favored to win Wednesday's MLB matchup [9/17/2025]

The New York Mets and San Diego Padres will lock horns in MLB action at Citi Field on Wednesday, starting at 7:10PM ET.

David Peterson (9-5, 3.77 ERA) will be on the bump for the Mets, while the Padres are going with Nick Pivetta (13-5, 2.73 ERA).

Based on updated simulation results, Dimers' advanced MLB model predicts the Mets as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Padres-Mets game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Mets' chance of winning at 56%, with the Padres at 44%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Padres vs. Mets predictions page.

Mets vs. Padres prediction: Who will win?

Using powerful machine learning and data analysis, we have simulated the result of Wednesday's MLB game between the Padres and Mets 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Mets a 56% chance of defeating the Padres.

According to our model, the over/under total of 7.5 runs has a 52% chance of going over.

Padres vs. Mets odds [9/17/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Padres	Mets
Moneyline	+105	-122
Total	o7.5 (+101)	u7.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Padres vs. Mets picks and best bets

Our model's biggest edge in today's Padres vs. Mets matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free MLB picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Padres vs. Mets game-day updates and essential details

Wednesday's MLB action between the Mets and Padres at Citi Field is scheduled to start at 7:10PM ET.

• Who: San Diego Padres vs. New York Mets
• Date: Wednesday, September 17, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Citi Field

Dimers' comprehensive preview of Wednesday's Padres vs. Mets matchup includes our prediction, picks and the latest betting odds.

Before making any Padres vs. Mets picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Mets, with a 56% win probability, will likely beat the Padres on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Mets insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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