Padres vs. Mets prediction: Mets favored to win Wednesday's MLB matchup [9/17/2025]

The New York Mets will take on the San Diego Padres in MLB action at Citi Field on Wednesday, beginning at 7:10PM ET.

The Mets will have David Peterson (9-5, 3.77 ERA) as their starting pitcher, pitting him against Nick Pivetta (13-5, 2.73 ERA) for the Padres.

Based on the latest simulation results, Dimers' proven MLB model predicts the Mets as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Padres-Mets game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Mets' chance of winning at 56%, with the Padres at 44%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Padres vs. Mets predictions page.

Mets vs. Padres prediction: Who will win?

Using powerful machine learning and data, we have simulated the result of Wednesday's MLB game between the Padres and Mets 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Mets a 56% chance of beating the Padres.

According to our model, the 7.5-run over/under has a 52% chance of going over.

Padres vs. Mets odds [9/17/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Padres	Mets
Moneyline	+105	-122
Total	o7.5 (+101)	u7.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Padres vs. Mets picks and best bets

Our model's biggest edge in today's Padres vs. Mets matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Padres vs. Mets game-day updates and essential details

Wednesday's MLB game between the Mets and Padres at Citi Field is scheduled to begin at 7:10PM ET.

• Who: San Diego Padres vs. New York Mets
• Date: Wednesday, September 17, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Citi Field

Dimers' in-depth preview of Wednesday's Padres vs. Mets matchup includes our prediction, picks and the latest betting odds.

Before making any Padres vs. Mets picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Mets, with a 56% win probability, will likely beat the Padres on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Mets insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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