Padres vs. Dodgers Prediction: Dodgers Predicted to Win Wednesday's MLB Matchup [6/18/2025]

The Los Angeles Dodgers will square off with the San Diego Padres in MLB action at Dodger Stadium on Wednesday, beginning at 10:10PM ET.

Emmet Sheehan (0-0, 0.00 ERA) will start on the mound for the Dodgers, while the Padres have opted for Stephen Kolek (3-2, 3.50 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Dodgers as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's San Diego-LA Dodgers game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Dodgers' chance of winning at 64%, with the Padres at 36%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Padres vs. Dodgers predictions page.

Dodgers vs. Padres Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the outcome of Wednesday's MLB matchup between the Padres and Dodgers 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Dodgers a 64% chance of beating the Padres.

According to our model, the Padres (+1.5) have a 55% chance of covering the run line, while the 9.5-run over/under has a 55% chance of staying under.

Padres vs. Dodgers Odds [6/18/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Padres	Dodgers
Run Line	+1.5 (-118)	-1.5 (+100)
Moneyline	+168	-198
Total	o9.5 (-114)	u9.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Padres vs. Dodgers Picks and Best Bets

Our model's biggest edge in today's Padres vs. Dodgers matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Padres vs. Dodgers Game-Day Updates and Essential Details

Wednesday's MLB action between the Dodgers and Padres at Dodger Stadium is scheduled to commence at 10:10PM ET.

• Who: San Diego Padres vs. Los Angeles Dodgers
• Date: Wednesday, June 18, 2025
• Time: 10:10PM ET/7:10PM PT
• Venue: Dodger Stadium

Dimers.com's full preview of Wednesday's Padres vs. Dodgers matchup includes our prediction, picks and the latest betting odds.

Before making any San Diego vs. LA Dodgers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Dodgers, with a 64% win probability, will likely beat the Padres on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Dodgers insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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