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Padres vs. Dodgers Prediction: Dodgers Predicted to Win Monday's MLB Matchup [6/16/2025]

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Written by Dave Garofolo

Our expert prediction for Monday's San Diego Padres vs Los Angeles Dodgers matchup.

San Diego Padres-Los Angeles Dodgers Predictions and Game Preview.
Dodger Stadium sets the stage for the MLB matchup between the San Diego Padres and Los Angeles Dodgers this Monday.

The Los Angeles Dodgers and San Diego Padres will meet in MLB action at Dodger Stadium on Monday, starting at 10:10PM ET.

Shohei Ohtani (0-0, 0.00 ERA) will start on the mound for the Dodgers, up against Dylan Cease (2-5, 4.28 ERA) for the Padres.

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Dodgers as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's San Diego-LA Dodgers game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Dodgers are likely to win, with a probability of 60%, compared to the Padres' 40%."

For a closer look at Monday's matchup, including best bets and picks, visit our interactive Padres vs. Dodgers predictions page.

Dodgers vs. Padres Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Monday's MLB matchup between the Padres and Dodgers 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Dodgers a 60% chance of defeating the Padres.

According to our model, the Padres (+1.5) have a 60% chance of covering the run line, while the over/under total of 9 runs has a 56% chance of staying under.

 

Padres vs. Dodgers Odds [6/16/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Padres Dodgers
Run Line +1.5 (-144) -1.5 (+120)
Moneyline +150 -162
Total o9 (-105) u9 (-110)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Padres vs. Dodgers Picks and Best Bets

Our model's strongest edge in today's Padres vs. Dodgers matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Padres vs. Dodgers Game-Day Updates and Essential Details

Monday's MLB game between the Dodgers and Padres at Dodger Stadium is scheduled to commence at 10:10PM ET.

Dimers.com's comprehensive preview of Monday's Padres vs. Dodgers matchup includes our prediction, picks and the latest betting odds.

Before making any San Diego vs. LA Dodgers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Dodgers, with a 60% win probability, will likely beat the Padres on Monday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Dodgers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the most accurate projections for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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