Padres vs. Reds Prediction: Cincinnati Predicted to Win Sunday's MLB Matchup [6/29/2025]

The Cincinnati Reds and San Diego Padres are scheduled to meet in MLB action at Great American Ball Park on Sunday, starting at 1:40PM ET.

Nick Lodolo (5-5, 3.63 ERA) will be the starting pitcher for the Reds, while the Padres have opted for Stephen Kolek (3-3, 3.95 ERA).

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Reds as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Padres-Reds game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Reds with a win probability of 55%, while the Padres have 45%."

For a closer look at Sunday's matchup, including best bets and picks, visit our interactive Padres vs. Reds predictions page.

Reds vs. Padres Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Sunday's MLB game between the Padres and Reds 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Reds a 55% chance of beating the Padres.

According to our model, the Padres (+1.5) have a 63% chance of covering the run line, while the 9-run over/under has a 53% chance of staying under.

Padres vs. Reds Odds [6/29/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Padres	Reds
Run Line	+1.5 (-176)	-1.5 (+155)
Moneyline	+116	-130
Total	o9 (-118)	u9 (+100)

All odds are correct at the time of publication and are subject to change.

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Padres vs. Reds Picks and Best Bets

Our model's biggest edge in today's Padres vs. Reds matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Padres vs. Reds Game-Day Updates and Essential Details

Sunday's MLB game between the Reds and Padres at Great American Ball Park is scheduled to commence at 1:40PM ET.

• Who: San Diego Padres vs. Cincinnati Reds
• Date: Sunday, June 29, 2025
• Time: 1:40PM ET/10:40AM PT
• Venue: Great American Ball Park

Dimers.com's in-depth preview of Sunday's Padres vs. Reds matchup includes our prediction, picks and the latest betting odds.

Before making any Padres vs. Reds picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Reds, with a 55% win probability, will likely beat the Padres on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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