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Padres vs. Diamondbacks Prediction: Arizona Predicted to Win Friday's MLB Matchup [6/13/2025]

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Written by Dave Garofolo

Our expert prediction for Friday's San Diego Padres vs Arizona Diamondbacks matchup.

San Diego Padres-Arizona Diamondbacks Predictions and Game Preview.
Chase Field sets the stage for the MLB matchup between the San Diego Padres and Arizona Diamondbacks this Friday.

The Arizona Diamondbacks will square off with the San Diego Padres in MLB action at Chase Field on Friday, starting at 9:40PM ET.

The Diamondbacks will have Ryne Nelson (2-2, 4.60 ERA) as their starting pitcher, while the Padres are going with Stephen Kolek (3-1, 3.00 ERA).

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Diamondbacks as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's San Diego-Arizona game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Diamondbacks' chance of winning is 56%, while the Padres' is 44%."

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Padres vs. Diamondbacks predictions page.

Diamondbacks vs. Padres Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Friday's MLB matchup between the Padres and Diamondbacks 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Diamondbacks a 56% chance of beating the Padres.

According to our model, the Padres (+1.5) have a 62% chance of covering the run line, while the over/under total of 9.5 runs has a 51% chance of staying under.

 

Padres vs. Diamondbacks Odds [6/13/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Padres Diamondbacks
Run Line +1.5 (-176) -1.5 (+155)
Moneyline +120 -136
Total o9.5 (+100) u9.5 (-112)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Padres vs. Diamondbacks Picks and Best Bets

Our model's strongest edge in today's Padres vs. Diamondbacks matchup is on the over/under.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Padres vs. Diamondbacks Game-Day Updates and Essential Details

Friday's MLB matchup between the Diamondbacks and Padres at Chase Field is scheduled to begin at 9:40PM ET.

Dimers.com's in-depth preview of Friday's Padres vs. Diamondbacks matchup includes our prediction, picks and the latest betting odds.

Before making any San Diego vs. Arizona picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Diamondbacks, with a 56% win probability, will likely beat the Padres on Friday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Diamondbacks insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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