Roman Safiullin vs. Holger Rune Prediction, Odds, Picks for ATP Cincinnati Open 2025

Roman Safiullin and Holger Rune will lock horns in the round of 64 of the ATP Cincinnati Open event on Saturday.

Based on updated simulations, Dimers' advanced tennis model (see Dimers Pro for full access) projects Holger Rune as the most likely winner of the match.

For expanded analysis of Saturday's match, including best bets and picks, visit our interactive Safiullin vs. Rune predictions page.

Safiullin vs. Rune Prediction: Who Will Win and Advance to the Round of 32?

Using trusted machine learning and data, we have simulated the result of Saturday's Safiullin-Rune men's singles match 10,000 times as part of our tennis predictions coverage.

Our leading predictive model gives Rune a 64% chance of winning against Safiullin at the ATP Cincinnati Open tournament.

Additionally, Rune has a 61% chance of winning the first set, according to our model.

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Roman Safiullin vs. Holger Rune Odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Safiullin	Rune
Moneyline	+250	-333
First Set	+200	-250

All odds are correct at the time of publication and are subject to change.

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Safiullin vs. Rune Picks and Best Bets

Our model's strongest edge in today's Safiullin vs. Rune match is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best tennis picks and tennis best bets for every match throughout the year.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Safiullin vs. Rune Updates and Essential Details

The ATP Cincinnati Open match between Roman Safiullin and Holger Rune is scheduled to begin on Saturday at 11:00AM ET.

• Who: Roman Safiullin vs. Holger Rune
• Date: Saturday, August 9, 2025
• Approx. Time: 11:00AM ET/8:00AM PT
• Tournament: ATP Cincinnati, USA Men's Singles 2025
• Round: Round of 64

All dates and times in this article are United States Eastern Time unless otherwise noted.

Dimers.com's in-depth preview of Saturday's Safiullin vs. Rune match includes our prediction, picks and the latest betting odds.

Before making any Roman Safiullin vs. Holger Rune picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

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Conclusion

We predict Holger Rune, with a 64% win probability, will likely beat Roman Safiullin at the ATP Cincinnati Open tournament.

AI and automation have enhanced this article to quickly deliver accurate Safiullin vs. Rune insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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