Reilly Opelka vs. Francisco Comesana Prediction, Odds, Picks for ATP Cincinnati Open 2025

Reilly Opelka and Francisco Comesana are scheduled to meet in the round of 32 of the ATP Cincinnati Open event on Tuesday.

Based on the latest simulation results, Dimers' advanced tennis model (see Dimers Pro for full access) projects Reilly Opelka as the most likely winner of the match.

For further insights into Tuesday's match, including best bets and picks, visit our interactive Opelka vs. Comesana predictions page.

Opelka vs. Comesana Prediction: Who Will Win and Advance to the Round of 16?

Using trusted machine learning and data, we have simulated the outcome of Tuesday's Opelka-Comesana men's singles match 10,000 times as part of our tennis predictions coverage.

Our leading predictive model gives Opelka a 59% chance of winning against Comesana at the ATP Cincinnati Open tournament.

Additionally, Opelka has a 57% chance of winning the first set, according to our model.

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Reilly Opelka vs. Francisco Comesana Odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Opelka	Comesana
Moneyline	-200	+162
First Set	-175	+137

All odds are correct at the time of publication and are subject to change.

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Opelka vs. Comesana Picks and Best Bets

Our model's biggest edge in today's Opelka vs. Comesana match is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Opelka vs. Comesana Updates and Essential Details

The ATP Cincinnati Open match between Reilly Opelka and Francisco Comesana is scheduled to commence on Tuesday at 11:00AM ET.

• Who: Reilly Opelka vs. Francisco Comesana
• Date: Tuesday, August 12, 2025
• Approx. Time: 11:00AM ET/8:00AM PT
• Tournament: ATP Cincinnati, USA Men's Singles 2025
• Round: Round of 32

All dates and times in this article are United States Eastern Time unless otherwise stated.

Dimers.com's full preview of Tuesday's Opelka vs. Comesana match includes our prediction, picks and the latest betting odds.

Before making any Reilly Opelka vs. Francisco Comesana picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

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Conclusion

We predict Reilly Opelka, with a 59% win probability, will likely beat Francisco Comesana at the ATP Cincinnati Open tournament.

AI and automation have enhanced this article to quickly deliver accurate Opelka vs. Comesana insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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