Pittsburgh vs. West Virginia prediction: Why Pittsburgh is favored to win in college football Week 3, 2025

West Virginia will take on the favored Pittsburgh in Week 3 college football action at Mountaineer Field at Milan Puskar Stadium on Saturday, commencing at 3:30PM ET.

Based on updated simulations, Dimers' proven college football model projects Pittsburgh as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Pittsburgh vs. West Virginia predictions page.

Pittsburgh vs. West Virginia prediction: Who will win, cover the spread?

Using innovative machine learning and statistical analysis, we have simulated the result of Pittsburgh vs. West Virginia 10,000 times as part of our college football predictions coverage.

Our leading predictive model currently gives Pittsburgh a 68% chance of defeating West Virginia. Our predicted final score has Pittsburgh winning 31-23.

According to our model, the bookmakers have got it right, and Pittsburgh and West Virginia each have a 50% chance of covering the spread, while the over/under total of 54.5 points has a 55% chance of going over.

Pittsburgh vs. West Virginia odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Pittsburgh	West Virginia
Spread	-7.5 (-105)	+7.5 (-115)
Moneyline	-270	+240
Total	o54.5 (-110)	u54.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Pittsburgh vs. West Virginia picks and best bets

Our model's strongest edge in today's Pittsburgh vs. West Virginia matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Pittsburgh vs. West Virginia game-day updates and essential details

Saturday's college football game between West Virginia and Pittsburgh at Mountaineer Field at Milan Puskar Stadium is scheduled to commence at 3:30PM ET.

• Who: Pittsburgh vs. West Virginia
• Date: Saturday, September 13, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: Mountaineer Field at Milan Puskar Stadium

Dimers' comprehensive preview of Saturday's Pittsburgh vs. West Virginia matchup includes our prediction, picks and the latest betting odds.

Before making any Pittsburgh vs. West Virginia picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Pittsburgh, with a 68% win probability, will likely beat West Virginia on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Pittsburgh vs. West Virginia insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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