Pittsburgh vs. Louisville Prediction: Louisville Predicted to Win College Basketball Matchup [3/1/2025]

Louisville will square off with Pittsburgh in college basketball action at KFC Yum! Center on Saturday, beginning at 6:00PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model (see Dimers Pro for full access) predicts Louisville as the most likely winner of today's game.

Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities.

"Our team has used the latest data to run 10,000 simulations of Saturday's Pittsburgh-Louisville game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that Louisville is more likely to win, while Pittsburgh has a lower chance of victory."

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Pittsburgh vs. Louisville predictions page.

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Pittsburgh vs. Louisville Prediction: Who Will Win, Cover the Spread?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball matchup between Pittsburgh and Louisville 10,000 times as part of our college basketball predictions coverage.

Our famous predictive model currently gives Louisville an 85% chance of defeating Pittsburgh. Our predicted final score has Louisville winning 81-70.

According to our model, Louisville (-10.5) has a 54% chance of covering the spread, while the over/under total of 149.5 points has a 51% chance of staying under.

Pittsburgh vs. Louisville Odds

We have sourced the best College Basketball odds in America for this game, which are listed here:

Bet Type	Pittsburgh	Louisville
Spread	+10.5 (-110)	-10.5 (-105)
Moneyline	+455	-550
Total	o149.5 (-115)	u149.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Pittsburgh vs. Louisville Picks and Best Bets

Our model's strongest edge in today's Pittsburgh vs. Louisville matchup is on the over/under.

Our expert predictions, aligned with the best odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Pittsburgh vs. Louisville Game-Day Updates and Essential Details

Saturday's college basketball action between Louisville and Pittsburgh at KFC Yum! Center is scheduled to commence at 6:00PM ET.

• Who: Pittsburgh vs. Louisville
• Date: Saturday, March 1, 2025
• Time: 6:00PM ET/3:00PM PT
• Venue: KFC Yum! Center

Dimers.com's full preview of Saturday's Pittsburgh vs. Louisville matchup includes our prediction, picks and the latest betting odds.

Before making any Pittsburgh vs. Louisville picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

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Conclusion

We predict Louisville, with an 85% win probability, will likely beat Pittsburgh on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Pittsburgh vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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