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Pittsburgh Steelers vs. Buffalo Bills NFL Betting Picks, Predictions and Props: Sunday September 12, 2021
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
The game of the early slate comes in the form of the Buffalo Bills hosting the Pittsburgh Steelers this week, with Josh Allen looking to begin what should be an MVP-caliber season.
The 2021 NFL season continues on Sunday September 12, 2021, and, as always, Dimers.com has simulated Steelers vs. Bills 10,000 times to determine where the value lies for football bettors across the United States.
With NFL betting picks, probabilities, odds and predicted scores featured each and every week at Dimers, check out our top plays for this NFL 2021 Week 1 matchup.
Today's NFL best bets and odds are proudly brought to you by TwinSpires Sportsbook.
NFL 2021 Week 1: Steelers vs. Bills
💰 Best Bet
These two teams are going in different directions. The Bills look set to take another step forward this season and compete for the Super Bowl, whilst the Steelers are on a downward trajectory after starting last season 12-0.
Josh Allen and Stefon Diggs form one of the best QB-WR duos in the league and along with other offensive weapons like Devin Singletary, Zack Moss and Cole Beasley, they should be able to overpower Pittsburgh and win this by more than a tuddy.
You can see all live probabilities in the interactive widget below. Remember, our predictive analytics model is constantly simulating every NFL matchup to find the best value on the spread, moneyline, over/under and player props!
PICK: Bills to cover @ TwinSpires (-109)
🔥 Best Player Prop
Although the above was all about the Bills, and in particular, the Allen-Diggs connection, the best prop play in this game appears to come on the other end, with the Roethlisberger-Claypool connection.
At the time of writing, DimersBOT is projecting the NFL sophomore to go for 72 yards, which is well above the line being set by the books!
PICK: Chase Claypool OVER 52.5 receiving yards @ TwinSpires (-112)
TwinSpires not available in your state? We recommend PointsBet Sportsbook as the next best option. Claim $101 in FREE bets with PointsBet Sportsbook by depositing $10!
🎁 Best Sportsbook Promo
The Bills come into this game as favorites (as they should) meaning there isn't a lot of value betting them at the moneyline. But, that doesn't mean there isn't a nice and easy way to cash in on them getting the dub in this one!
If you place a $50 bet on Buffalo to win the Super Bowl with Twinspires Sportsbook, you'll score yourself $10 every time they win this season. Yep, even if they don't win the big one, you'll be in the black as soon as they win their fifth game of the season (they won 13 last year)!
CLAIM: TwinSpires Super Bowl promotion
As it stands, our model has the Bills as the third best chance of winning the Super Bowl this season, but if you're feeling any other team you can check out the Super Bowl probabilities for every team in the NFL.
MORE: Steelers vs. Bills picks and predictions
NFL 2021 Week 1 Schedule
Thursday September 9, 2021
Sunday September 12, 2021
- Philadelphia Eagles at Atlanta Falcons, 1PM ET
- Pittsburgh Steelers at Buffalo Bills, 1PM ET
- New York Jets at Carolina Panthers, 1PM ET
- Minnesota Vikings at Cincinnati Bengals, 1PM ET
- San Francisco 49ers at Detroit Lions, 1PM ET
- Jacksonville Jaguars at Houston Texans, 1PM ET
- Seattle Seahawks at Indianapolis Colts, 1PM ET
- Arizona Cardinals at Tennessee Titans, 1PM ET
- Los Angeles Chargers at Washington Football Team, 1PM ET
- Cleveland Browns at Kansas City Chiefs, 4:25PM ET
- Miami Dolphins at New England Patriots, 4:25PM ET
- Green Bay Packers at New Orleans Saints, 4:25PM ET
- Denver Broncos at New York Giants, 4:25PM ET
- Chicago Bears at Los Angeles Rams, 8:20PM ET (Sunday Night Football)
Monday September 13, 2021
Ready to join a sportsbook but TwinSpires isn't available in your state yet? Check out the best sports betting promos available in your state.
Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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