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Pirates vs. Giants Prediction: San Francisco Predicted to Win Monday's MLB Matchup [7/28/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Our expert prediction for Monday's Pittsburgh Pirates vs San Francisco Giants matchup.
The San Francisco Giants will face the Pittsburgh Pirates in MLB action at Oracle Park on Monday, beginning at 9:45PM ET.
Carson Whisenhunt (0-0, 0.00 ERA) will be the starting pitcher for the Giants, pitting him against Mitch Keller (4-10, 3.53 ERA) for the Pirates.
Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Giants as the most likely winner of today's game.
For a closer look at Monday's matchup, including best bets and picks, visit our interactive Pirates vs. Giants predictions page.
Giants vs. Pirates Prediction: Who Will Win, Cover the Run Line?
Using powerful machine learning and data, we have simulated the outcome of Monday's MLB matchup between the Pirates and Giants 10,000 times as part of our MLB predictions coverage.
Our leading predictive model currently gives the Giants a 55% chance of defeating the Pirates.
According to our model, the Pirates (+1.5) have a 65% chance of covering the run line, while the over/under total of 7.5 runs has a 51% chance of staying under.
Pirates vs. Giants Odds [7/28/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Pirates | Giants |
|---|---|---|
| Run Line | +1.5 (-194) | -1.5 (+167) |
| Moneyline | +116 | -135 |
| Total | o7.5 (-117) | u7.5 (-102) |
All odds are correct at the time of publication and are subject to change.
Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.
Pirates vs. Giants Picks and Best Bets
Our model's biggest edge in today's Pirates vs. Giants matchup is on the run line.
Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our full set of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Best Bets Today
Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.
Pirates vs. Giants Game-Day Updates and Essential Details
Monday's MLB matchup between the Giants and Pirates at Oracle Park is scheduled to commence at 9:45PM ET.
- Who: Pittsburgh Pirates vs. San Francisco Giants
- Date: Monday, July 28, 2025
- Time: 9:45PM ET/6:45PM PT
- Venue: Oracle Park
Dimers.com's full preview of Monday's Pirates vs. Giants matchup includes our prediction, picks and the latest betting odds.
Before making any Pirates vs. Giants picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Conclusion
We predict the Giants, with a 55% win probability, will likely beat the Pirates on Monday.
AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Giants insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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