Pirates vs. Phillies Prediction: Philadelphia Predicted to Win Saturday's MLB Matchup [5/17/2025]

MLB action continues on Saturday at 6:05PM ET as the Pittsburgh Pirates square off with the Philadelphia Phillies at Citizens Bank Park.

The Phillies will send Zack Wheeler (4-1, 2.95 ERA) to the mound, up against Carmen Mlodzinski (1-3, 5.20 ERA) for the Pirates.

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Phillies as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Pittsburgh-Philadelphia game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Phillies are more likely to win, while the Pirates have a lower chance of victory."

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Pirates vs. Phillies predictions page.

Phillies vs. Pirates Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Saturday's MLB game between the Pirates and Phillies 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Phillies a 71% chance of beating the Pirates.

According to our model, the Phillies (-1.5) have a 55% chance of covering the run line, while the over/under total of 9 runs has a 54% chance of staying under.

Pirates vs. Phillies Odds [5/17/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Pirates	Phillies
Run Line	+1.5 (+140)	-1.5 (-164)
Moneyline	+270	-320
Total	o9 (-112)	u9 (-102)

All odds are correct at the time of publication and are subject to change.

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Pirates vs. Phillies Picks and Best Bets

Our model's strongest edge in today's Pirates vs. Phillies matchup is on the total.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Pirates vs. Phillies Game-Day Updates and Essential Details

Saturday's MLB matchup between the Phillies and Pirates at Citizens Bank Park is scheduled to commence at 6:05PM ET.

• Who: Pittsburgh Pirates vs. Philadelphia Phillies
• Date: Saturday, May 17, 2025
• Time: 6:05PM ET/3:05PM PT
• Venue: Citizens Bank Park

Dimers.com's full preview of Saturday's Pirates vs. Phillies matchup includes our prediction, picks and the latest betting odds.

Before making any Pittsburgh vs. Philadelphia picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Phillies, with a 71% win probability, will likely beat the Pirates on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Phillies insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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