Pirates vs. Brewers Prediction: Milwaukee Predicted to Win Wednesday's MLB Matchup [8/13/2025]

The Milwaukee Brewers will take on the Pittsburgh Pirates in MLB action at American Family Field on Wednesday, commencing at 2:10PM ET.

The Brewers will start Brandon Woodruff (4-0, 2.29 ERA), while the Pirates are going with Mitch Keller (5-10, 3.86 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Brewers as the most likely winner of today's game. "Our team has simulated the outcome of Wednesday's Pirates-Brewers game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Brewers' chance of winning at 68%, with the Pirates at 32%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Pirates vs. Brewers predictions page.

Brewers vs. Pirates Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the result of Wednesday's MLB matchup between the Pirates and Brewers 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Brewers a 68% chance of defeating the Pirates.

According to our model, the Pirates (+1.5) have a 52% chance of covering the run line, while the over/under total of 7 runs has a 51% chance of going over.

Pirates vs. Brewers Odds [8/13/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Pirates	Brewers
Run Line	+1.5 (+100)	-1.5 (-118)
Moneyline	+205	-250
Total	o7 (-120)	u7 (+100)

All odds are correct at the time of publication and are subject to change.

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Pirates vs. Brewers Picks and Best Bets

Our model's biggest edge in today's Pirates vs. Brewers matchup is on the total.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Pirates vs. Brewers Game-Day Updates and Essential Details

Wednesday's MLB action between the Brewers and Pirates at American Family Field is scheduled to begin at 2:10PM ET.

• Who: Pittsburgh Pirates vs. Milwaukee Brewers
• Date: Wednesday, August 13, 2025
• Time: 2:10PM ET/11:10AM PT
• Venue: American Family Field

Dimers.com's full preview of Wednesday's Pirates vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Pirates vs. Brewers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Brewers, with a 68% win probability, will likely beat the Pirates on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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