Pirates vs. Brewers Prediction: Milwaukee Predicted to Win Tuesday's MLB Matchup [8/12/2025]

The Milwaukee Brewers will square off with the Pittsburgh Pirates in MLB action at American Family Field on Tuesday, commencing at 7:40PM ET.

The Brewers will send Freddy Peralta (13-5, 3.03 ERA) to the mound, pitting him against Paul Skenes (7-8, 1.94 ERA) for the Pirates.

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Brewers as the most likely winner of today's game.

For a closer look at Tuesday's matchup, including best bets and picks, visit our interactive Pirates vs. Brewers predictions page.

Brewers vs. Pirates Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Tuesday's MLB game between the Pirates and Brewers 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Brewers a 55% chance of defeating the Pirates.

According to our model, the Pirates (+1.5) have a 66% chance of covering the run line, while the 6.5-run over/under has a 51% chance of going over.

Pirates vs. Brewers Odds [8/12/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Pirates	Brewers
Run Line	+1.5 (-200)	-1.5 (+168)
Moneyline	+118	-134
Total	o6.5 (-104)	u6.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Pirates vs. Brewers Picks and Best Bets

Our model's biggest edge in today's Pirates vs. Brewers matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Pirates vs. Brewers Game-Day Updates and Essential Details

Tuesday's MLB action between the Brewers and Pirates at American Family Field is scheduled to start at 7:40PM ET.

• Who: Pittsburgh Pirates vs. Milwaukee Brewers
• Date: Tuesday, August 12, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: American Family Field

Dimers.com's comprehensive preview of Tuesday's Pirates vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Pirates vs. Brewers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Brewers, with a 55% win probability, will likely beat the Pirates on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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