Pirates vs. Tigers Prediction: Detroit Predicted to Win Wednesday's MLB Matchup [6/18/2025]

The Detroit Tigers will square off with the Pittsburgh Pirates in MLB action at Comerica Park on Wednesday, starting at 6:40PM ET.

Tarik Skubal (7-2, 1.99 ERA) will be the starting pitcher for the Tigers, while the Pirates have opted for Andrew Heaney (3-5, 3.33 ERA).

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Tigers as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Pittsburgh-Detroit game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Tigers' chance of winning at 72%, with the Pirates at 28%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Pirates vs. Tigers predictions page.

Tigers vs. Pirates Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the result of Wednesday's MLB matchup between the Pirates and Tigers 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Tigers a 72% chance of beating the Pirates.

According to our model, the bookmakers have got it right, and the Pirates and Tigers each have a 50% chance of covering the run line, while the 6.5-run over/under has a 53% chance of going over.

Pirates vs. Tigers Odds [6/18/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Pirates	Tigers
Run Line	+1.5 (+120)	-1.5 (-130)
Moneyline	+260	-320
Total	o6.5 (-118)	u6.5 (+102)

All odds are correct at the time of publication and are subject to change.

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Pirates vs. Tigers Picks and Best Bets

Our model's strongest edge in today's Pirates vs. Tigers matchup is on the total.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Pirates vs. Tigers Game-Day Updates and Essential Details

Wednesday's MLB action between the Tigers and Pirates at Comerica Park is scheduled to commence at 6:40PM ET.

• Who: Pittsburgh Pirates vs. Detroit Tigers
• Date: Wednesday, June 18, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: Comerica Park

Dimers.com's in-depth preview of Wednesday's Pirates vs. Tigers matchup includes our prediction, picks and the latest betting odds.

Before making any Pittsburgh vs. Detroit picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Tigers, with a 72% win probability, will likely beat the Pirates on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Tigers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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