Pirates vs. Cubs prediction: Cubs predicted to win Sunday's MLB matchup [8/17/2025]

The Chicago Cubs will square off with the Pittsburgh Pirates in MLB action at Wrigley Field on Sunday, starting at 2:20PM ET.

The Cubs will send Javier Assad (0-1, 9.00 ERA) to the mound, while the Pirates will counter with Carmen Mlodzinski (2-7, 4.20 ERA).

Based on updated simulations, Dimers' advanced MLB model projects the Cubs as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Pirates-Cubs game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Cubs with a win probability of 63%, while the Pirates have 37%."

For further insights into Sunday's matchup, including best bets and picks, visit our interactive Pirates vs. Cubs predictions page.

Cubs vs. Pirates prediction: Who will win, cover the run line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Sunday's MLB matchup between the Pirates and Cubs 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Cubs a 63% chance of defeating the Pirates.

According to our model, the Pirates (+1.5) have a 56% chance of covering the run line, while the over/under total of 7.5 runs has a 51% chance of going over.

Pirates vs. Cubs odds [8/17/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Pirates	Cubs
Run Line	+1.5 (-132)	-1.5 (+115)
Moneyline	+168	-190
Total	o7.5 (+105)	u7.5 (-136)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Pirates vs. Cubs picks and best bets

Our model's biggest edge in today's Pirates vs. Cubs matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets today

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Pirates vs. Cubs game-day updates and essential details

Sunday's MLB action between the Cubs and Pirates at Wrigley Field is scheduled to begin at 2:20PM ET.

• Who: Pittsburgh Pirates vs. Chicago Cubs
• Date: Sunday, August 17, 2025
• Time: 2:20PM ET/11:20AM PT
• Venue: Wrigley Field

Dimers.com's comprehensive preview of Sunday's Pirates vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Pirates vs. Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Cubs, with a 63% win probability, will likely beat the Pirates on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.