Pirates vs. Cubs Prediction: Cubs Predicted to Win Friday's MLB Matchup [6/13/2025]

The Chicago Cubs will take on the Pittsburgh Pirates, in what is expected to be a close MLB game, at Wrigley Field on Friday, starting at 2:20PM ET.

Cade Horton (3-1, 4.11 ERA) will get the ball for the Cubs, while the Pirates have opted for Paul Skenes (4-6, 1.88 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Cubs as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Pittsburgh-CHI Cubs game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Cubs' chance of winning is 53%, while the Pirates' is 47%."

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Pirates vs. Cubs predictions page.

Cubs vs. Pirates Prediction: Who Will Win?

Using trusted machine learning and data, we have simulated the result of Friday's MLB game between the Pirates and Cubs 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Cubs a 53% chance of beating the Pirates.

According to our model, the 6.5-run over/under has a 54% chance of going over.

Pirates vs. Cubs Odds [6/13/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Pirates	Cubs
Moneyline	-102	-116
Total	o6.5 (-115)	u6.5 (-102)

All odds are correct at the time of publication and are subject to change.

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Pirates vs. Cubs Picks and Best Bets

Our model's strongest edge in today's Pirates vs. Cubs matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Pirates vs. Cubs Game-Day Updates and Essential Details

Friday's MLB game between the Cubs and Pirates at Wrigley Field is scheduled to commence at 2:20PM ET.

• Who: Pittsburgh Pirates vs. Chicago Cubs
• Date: Friday, June 13, 2025
• Time: 2:20PM ET/11:20AM PT
• Venue: Wrigley Field

Dimers.com's comprehensive preview of Friday's Pirates vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Pittsburgh vs. CHI Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Cubs, with a 53% win probability, will likely beat the Pirates on Friday.

AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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