Pirates vs. Red Sox prediction: Boston favored to win Friday's MLB matchup [8/29/2025]

The Boston Red Sox will square off with the Pittsburgh Pirates in MLB action at Fenway Park on Friday, commencing at 7:10PM ET.

Payton Tolle (0-0, 0.00 ERA) will get the ball for the Red Sox, while the Pirates have opted for Paul Skenes (8-9, 2.07 ERA).

Based on updated simulation results, Dimers' advanced MLB model projects the Red Sox as the most likely winner of today's game.

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Pirates vs. Red Sox predictions page.

Red Sox vs. Pirates prediction: Who will win?

Using trusted machine learning and statistical analysis, we have simulated the result of Friday's MLB matchup between the Pirates and Red Sox 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Red Sox a 52% chance of beating the Pirates.

According to our model, the 8-run over/under has a 53% chance of staying under.

Pirates vs. Red Sox odds [8/29/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Pirates	Red Sox
Moneyline	+100	-115
Total	o8 (-105)	u8 (-115)

All odds are correct at the time of publication and are subject to change.

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Pirates vs. Red Sox picks and best bets

Our model's strongest edge in today's Pirates vs. Red Sox matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets video

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Pirates vs. Red Sox game-day updates and essential details

Friday's MLB matchup between the Red Sox and Pirates at Fenway Park is scheduled to start at 7:10PM ET.

• Who: Pittsburgh Pirates vs. Boston Red Sox
• Date: Friday, August 29, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Fenway Park

Dimers.com's in-depth preview of Friday's Pirates vs. Red Sox matchup includes our prediction, picks and the latest betting odds.

Before making any Pirates vs. Red Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Red Sox, with a 52% win probability, will likely beat the Pirates on Friday.

AI and automation have enhanced this article to quickly deliver accurate Pirates vs. Red Sox insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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