Phillies vs. Nationals prediction: Philadelphia predicted to win Saturday's MLB matchup [8/16/2025]

The Washington Nationals will square off with the Philadelphia Phillies, in what is expected to be a close MLB game, at Nationals Park on Saturday, starting at 4:05PM ET.

The Nationals will send Cade Cavalli (0-0, 3.86 ERA) to the mound, while the Phillies have opted for Taijuan Walker (4-5, 3.39 ERA).

Based on updated simulations, Dimers' advanced MLB model projects the Phillies as the most likely winner of today's game.

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Phillies vs. Nationals predictions page.

Nationals vs. Phillies prediction: Who will win, cover the run line?

Using trusted machine learning and data analysis, we have simulated the outcome of Saturday's MLB matchup between the Phillies and Nationals 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Phillies a 54% chance of defeating the Nationals.

According to our model, the Nationals (+1.5) have a 58% chance of covering the run line, while the over/under total of 10 runs has a 54% chance of staying under.

Phillies vs. Nationals odds [8/16/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Phillies	Nationals
Run Line	-1.5 (+108)	+1.5 (-125)
Moneyline	-142	+125
Total	o10 (-107)	u10 (-113)

All odds are correct at the time of publication and are subject to change.

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Phillies vs. Nationals picks and best bets

Our model's strongest edge in today's Phillies vs. Nationals matchup is on the over/under.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets today

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Phillies vs. Nationals game-day updates and essential details

Saturday's MLB game between the Nationals and Phillies at Nationals Park is scheduled to start at 4:05PM ET.

• Who: Philadelphia Phillies vs. Washington Nationals
• Date: Saturday, August 16, 2025
• Time: 4:05PM ET/1:05PM PT
• Venue: Nationals Park

Dimers.com's comprehensive preview of Saturday's Phillies vs. Nationals matchup includes our prediction, picks and the latest betting odds.

Before making any Phillies vs. Nationals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Phillies, with a 54% win probability, will likely beat the Nationals on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Phillies vs. Nationals insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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