Phillies vs. Cardinals Prediction: Philadelphia Predicted to Win Friday's MLB Matchup [4/11/2025]

The St. Louis Cardinals will take on the Philadelphia Phillies, in what is expected to be a close MLB game, at Busch Stadium on Friday, starting at 8:15PM ET.

Andre Pallante (1-0, 3.86 ERA) will start on the mound for the Cardinals, while the Phillies will counter with Aaron Nola (0-2, 6.35 ERA).

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Phillies as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Philadelphia-St. Louis game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Phillies' chance of winning is 52%, while the Cardinals' is 48%."

For further insights into Friday's matchup, including best bets and picks, visit our interactive Phillies vs. Cardinals predictions page.

Phillies vs. Phillies Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Friday's MLB matchup between the Phillies and Cardinals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Phillies a 52% chance of beating the Cardinals.

According to our model, the Cardinals (+1.5) have a 62% chance of covering the run line, while the over/under total of 7.5 runs has a 52% chance of going over.

Phillies vs. Cardinals Odds [4/11/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Phillies	Cardinals
Run Line	-1.5 (+150)	+1.5 (-175)
Moneyline	-116	-102
Total	o7.5 (-105)	u7.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Phillies vs. Cardinals Picks and Best Bets

Our model's strongest edge in today's Phillies vs. Cardinals matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Phillies vs. Cardinals Game-Day Updates and Essential Details

Friday's MLB matchup between the Cardinals and Phillies at Busch Stadium is scheduled to start at 8:15PM ET.

• Who: Philadelphia Phillies vs. St. Louis Cardinals
• Date: Friday, April 11, 2025
• Time: 8:15PM ET/5:15PM PT
• Venue: Busch Stadium

Dimers.com's in-depth preview of Friday's Phillies vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Philadelphia vs. St. Louis picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Phillies, with a 52% win probability, will likely beat the Cardinals on Friday.

AI and automation have enhanced this article to quickly deliver accurate Phillies vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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