Phillies vs. Pirates Prediction: Philadelphia Predicted to Win Friday's MLB Matchup [6/6/2025]

MLB action continues on Friday at 6:40PM ET as the Philadelphia Phillies square off with the Pittsburgh Pirates at PNC Park.

Bailey Falter (4-3, 3.14 ERA) will start on the mound for the Pirates, up against Joe Ross (2-1, 4.34 ERA) for the Phillies.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Phillies as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Philadelphia-Pittsburgh game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Phillies' chance of winning is 53%, while the Pirates' is 47%."

For a closer look at Friday's matchup, including best bets and picks, visit our interactive Phillies vs. Pirates predictions page.

Pirates vs. Phillies Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the outcome of Friday's MLB game between the Phillies and Pirates 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Phillies a 53% chance of beating the Pirates.

According to our model, the Pirates (+1.5) have a 59% chance of covering the run line, while the over/under total of 8.5 runs has a 51% chance of going over.

Phillies vs. Pirates Odds [6/6/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Phillies	Pirates
Run Line	-1.5 (+125)	+1.5 (-140)
Moneyline	-130	+112
Total	o8.5 (-120)	u8.5 (+104)

All odds are correct at the time of publication and are subject to change.

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Phillies vs. Pirates Picks and Best Bets

Our model's strongest edge in today's Phillies vs. Pirates matchup is on the total.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

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Phillies vs. Pirates Game-Day Updates and Essential Details

Friday's MLB action between the Pirates and Phillies at PNC Park is scheduled to commence at 6:40PM ET.

• Who: Philadelphia Phillies vs. Pittsburgh Pirates
• Date: Friday, June 6, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's full preview of Friday's Phillies vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any Philadelphia vs. Pittsburgh picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Phillies, with a 53% win probability, will likely beat the Pirates on Friday.

AI and automation have enhanced this article to quickly deliver accurate Phillies vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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