Phillies vs. Mets Prediction: Philadelphia Predicted to Win Tuesday's MLB Matchup [4/22/2025]

The New York Mets will face the Philadelphia Phillies in MLB action at Citi Field on Tuesday, starting at 7:10PM ET.

Griffin Canning (2-1, 3.43 ERA) will start for the Mets, while the Phillies have opted for Cristopher Sánchez (2-0, 2.96 ERA).

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Phillies as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Philadelphia-NY Mets game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Phillies with a win probability of 53%, compared to 47% for the Mets."

For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Phillies vs. Mets predictions page.

Mets vs. Phillies Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Tuesday's MLB game between the Phillies and Mets 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Phillies a 53% chance of defeating the Mets.

According to our model, the Mets (+1.5) have a 60% chance of covering the run line, while the 8-run over/under has an equal 50-50 chance of hitting.

Phillies vs. Mets Odds [4/22/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Phillies	Mets
Run Line	-1.5 (+130)	+1.5 (-150)
Moneyline	-130	+114
Total	o8 (-105)	u8 (-115)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Phillies vs. Mets Picks and Best Bets

Our model's biggest edge in today's Phillies vs. Mets matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Phillies vs. Mets Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Mets and Phillies at Citi Field is scheduled to begin at 7:10PM ET.

• Who: Philadelphia Phillies vs. New York Mets
• Date: Tuesday, April 22, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Citi Field

Dimers.com's in-depth preview of Tuesday's Phillies vs. Mets matchup includes our prediction, picks and the latest betting odds.

Before making any Philadelphia vs. NY Mets picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
• Understand where sports odds come from and how they're applied to baseball matchups
• Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
• Stay informed with where online sports betting is currently legal and which betting sites are safest to use
• Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on

Conclusion

We predict the Phillies, with a 53% win probability, will likely beat the Mets on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Phillies vs. Mets insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the most accurate projections for the World Series, American League, National League and each division.