Phillies vs. Brewers prediction: Why Philadelphia is favored to win Wednesday's MLB matchup [9/3/2025]

MLB action continues on Wednesday at 7:40PM ET as the Philadelphia Phillies square off with the Milwaukee Brewers at American Family Field.

The Brewers will start Jose Quintana (10-5, 3.69 ERA), pitting him against Aaron Nola (3-7, 6.47 ERA) for the Phillies.

Based on updated simulation results, Dimers' advanced MLB model predicts the Phillies as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Phillies-Brewers game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Phillies' chance of winning at 51%, with the Brewers at 49%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Phillies vs. Brewers predictions page.

Brewers vs. Phillies prediction: Who will win, cover the run line?

Using trusted machine learning and data, we have simulated the result of Wednesday's MLB game between the Phillies and Brewers 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Phillies a 51% chance of defeating the Brewers.

According to our model, the Brewers (+1.5) have a 62% chance of covering the run line, while the over/under total of 9 runs has a 51% chance of staying under.

Phillies vs. Brewers odds [9/3/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Phillies	Brewers
Run Line	-1.5 (+150)	+1.5 (-164)
Moneyline	-110	+102
Total	o9 (-102)	u9 (-115)

All odds are correct at the time of publication and are subject to change.

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Phillies vs. Brewers picks and best bets

Our model's strongest edge in today's Phillies vs. Brewers matchup is on the total.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Phillies vs. Brewers game-day updates and essential details

Wednesday's MLB action between the Brewers and Phillies at American Family Field is scheduled to begin at 7:40PM ET.

• Who: Philadelphia Phillies vs. Milwaukee Brewers
• Date: Wednesday, September 3, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: American Family Field

Dimers.com's full preview of Wednesday's Phillies vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Phillies vs. Brewers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Phillies, with a 51% win probability, will likely beat the Brewers on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Phillies vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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