Phillies vs. Marlins prediction: Why Philadelphia is favored to win Saturday's MLB matchup [9/6/2025]

The Miami Marlins and Philadelphia Phillies will lock horns in MLB action at loanDepot park on Saturday, starting at 4:10PM ET.

Sandy Alcantara (8-11, 5.66 ERA) will start on the mound for the Marlins, pitting him against Jesús Luzardo (12-6, 4.05 ERA) for the Phillies.

Based on the latest simulations, Dimers' advanced MLB model predicts the Phillies as the most likely winner of today's game.

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Phillies vs. Marlins predictions page.

Marlins vs. Phillies prediction: Who will win, cover the run line?

Using trusted machine learning and data analysis, we have simulated the outcome of Saturday's MLB game between the Phillies and Marlins 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Phillies a 60% chance of defeating the Marlins.

According to our model, the Marlins (+1.5) have a 54% chance of covering the run line, while the 8-run over/under has a 51% chance of staying under.

Phillies vs. Marlins odds [9/6/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Phillies	Marlins
Run Line	-1.5 (+112)	+1.5 (-125)
Moneyline	-154	+133
Total	o8 (-103)	u8 (-114)

All odds are correct at the time of publication and are subject to change.

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Phillies vs. Marlins picks and best bets

Our model's strongest edge in today's Phillies vs. Marlins matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets video

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Phillies vs. Marlins game-day updates and essential details

Saturday's MLB action between the Marlins and Phillies at loanDepot park is scheduled to begin at 4:10PM ET.

• Who: Philadelphia Phillies vs. Miami Marlins
• Date: Saturday, September 6, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: loanDepot park

Dimers.com's full preview of Saturday's Phillies vs. Marlins matchup includes our prediction, picks and the latest betting odds.

Before making any Phillies vs. Marlins picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Phillies, with a 60% win probability, will likely beat the Marlins on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Phillies vs. Marlins insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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