Phillies vs. Marlins prediction: Why Philadelphia is favored to win Friday's MLB matchup [9/5/2025]

MLB action continues on Friday at 7:10PM ET as the Philadelphia Phillies lock horns with the Miami Marlins at loanDepot park.

Valente Bellozo (1-3, 3.91 ERA) will get the ball for the Marlins, pitting him against Cristopher Sánchez (11-5, 2.66 ERA) for the Phillies.

Based on updated simulations, Dimers' advanced MLB model predicts the Phillies as the most likely winner of today's game.

For further insights into Friday's matchup, including best bets and picks, visit our interactive Phillies vs. Marlins predictions page.

Marlins vs. Phillies prediction: Who will win, cover the run line?

Using innovative machine learning and data analysis, we have simulated the result of Friday's MLB game between the Phillies and Marlins 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Phillies a 68% chance of defeating the Marlins.

According to our model, the Phillies (-1.5) have a 57% chance of covering the run line, while the 8-run over/under has a 53% chance of going over.

Phillies vs. Marlins odds [9/5/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Phillies	Marlins
Run Line	-1.5 (-139)	+1.5 (+118)
Moneyline	-228	+210
Total	o8 (-110)	u8 (-104)

All odds are correct at the time of publication and are subject to change.

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Phillies vs. Marlins picks and best bets

Our model's biggest edge in today's Phillies vs. Marlins matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Phillies vs. Marlins game-day updates and essential details

Friday's MLB action between the Marlins and Phillies at loanDepot park is scheduled to start at 7:10PM ET.

• Who: Philadelphia Phillies vs. Miami Marlins
• Date: Friday, September 5, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: loanDepot park

Dimers.com's in-depth preview of Friday's Phillies vs. Marlins matchup includes our prediction, picks and the latest betting odds.

Before making any Phillies vs. Marlins picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Phillies, with a 68% win probability, will likely beat the Marlins on Friday.

AI and automation have enhanced this article to quickly deliver accurate Phillies vs. Marlins insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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