Phillies vs. Dodgers prediction: Dodgers favored to win Tuesday's MLB matchup [9/16/2025]

The Los Angeles Dodgers will face the Philadelphia Phillies in MLB action at Dodger Stadium on Tuesday, commencing at 10:10PM ET.

Shohei Ohtani (1-1, 3.75 ERA) will be the starting pitcher for the Dodgers, up against Cristopher Sánchez (13-5, 2.57 ERA) for the Phillies.

Based on updated simulations, Dimers' advanced MLB model projects the Dodgers as the most likely winner of today's game.

For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Phillies vs. Dodgers predictions page.

Dodgers vs. Phillies prediction: Who will win, cover the run line?

Using powerful machine learning and data, we have simulated the outcome of Tuesday's MLB matchup between the Phillies and Dodgers 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Dodgers a 55% chance of beating the Phillies.

According to our model, the Phillies (+1.5) have a 64% chance of covering the run line, while the 7.5-run over/under has a 53% chance of going over.

Phillies vs. Dodgers odds [9/16/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Phillies	Dodgers
Run Line	+1.5 (-196)	-1.5 (+165)
Moneyline	+112	-130
Total	o7.5 (-113)	u7.5 (-104)

All odds are correct at the time of publication and are subject to change.

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Phillies vs. Dodgers picks and best bets

Our model's strongest edge in today's Phillies vs. Dodgers matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets today

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Phillies vs. Dodgers game-day updates and essential details

Tuesday's MLB matchup between the Dodgers and Phillies at Dodger Stadium is scheduled to begin at 10:10PM ET.

• Who: Philadelphia Phillies vs. Los Angeles Dodgers
• Date: Tuesday, September 16, 2025
• Time: 10:10PM ET/7:10PM PT
• Venue: Dodger Stadium

Dimers' full preview of Tuesday's Phillies vs. Dodgers matchup includes our prediction, picks and the latest betting odds.

Before making any Phillies vs. Dodgers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Dodgers, with a 55% win probability, will likely beat the Phillies on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Phillies vs. Dodgers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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