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Phillies vs. Guardians Prediction: Philadelphia Predicted to Win Sunday's MLB Matchup [5/11/2025]

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Written by Jason Bevilacqua

Our expert prediction for Sunday's Philadelphia Phillies vs Cleveland Guardians matchup.

Philadelphia Phillies-Cleveland Guardians Predictions and Game Preview.
Progressive Field sets the stage for the MLB matchup between the Philadelphia Phillies and Cleveland Guardians this Sunday.

The Cleveland Guardians and Philadelphia Phillies will meet in MLB action at Progressive Field on Sunday, starting at 7:10PM ET.

Luis L. Ortiz (2-3, 5.30 ERA) will start for the Guardians, while the Phillies are going with Zack Wheeler (3-1, 3.35 ERA).

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Phillies as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Philadelphia-Cleveland game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Phillies with a win probability of 59%, while the Guardians have 41%."

For a closer look at Sunday's matchup, including best bets and picks, visit our interactive Phillies vs. Guardians predictions page.

Guardians vs. Phillies Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the outcome of Sunday's MLB game between the Phillies and Guardians 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Phillies a 59% chance of beating the Guardians.

According to our model, the Guardians (+1.5) have a 55% chance of covering the run line, while the 7.5-run over/under has a 52% chance of going over.

 

Phillies vs. Guardians Odds [5/11/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Phillies Guardians
Run Line -1.5 (+102) +1.5 (-110)
Moneyline -170 +150
Total o7.5 (+102) u7.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Phillies vs. Guardians Picks and Best Bets

Our model's strongest edge in today's Phillies vs. Guardians matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Phillies vs. Guardians Game-Day Updates and Essential Details

Sunday's MLB action between the Guardians and Phillies at Progressive Field is scheduled to begin at 7:10PM ET.

Dimers.com's in-depth preview of Sunday's Phillies vs. Guardians matchup includes our prediction, picks and the latest betting odds.

Before making any Philadelphia vs. Cleveland picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Phillies, with a 59% win probability, will likely beat the Guardians on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Phillies vs. Guardians insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay up-to-date with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the most up-to-date projections for the World Series, American League, National League and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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