Phillies vs. Diamondbacks prediction: Why Arizona is favored to win Saturday's MLB matchup [9/20/2025]

The Arizona Diamondbacks and Philadelphia Phillies will meet in MLB action at Chase Field on Saturday, starting at 8:10PM ET.

Zac Gallen (12-14, 4.73 ERA) will be on the bump for the Diamondbacks, pitting him against Aaron Nola (4-9, 6.44 ERA) for the Phillies.

Based on the latest simulations, Dimers' advanced MLB model projects the Diamondbacks as the most likely winner of today's game.

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Phillies vs. Diamondbacks predictions page.

Diamondbacks vs. Phillies prediction: Who will win?

Using innovative machine learning and data, we have simulated the outcome of Saturday's MLB matchup between the Phillies and Diamondbacks 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Diamondbacks a 51% chance of defeating the Phillies.

According to our model, the 9-run over/under has a 54% chance of going over.

Phillies vs. Diamondbacks odds [9/20/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Phillies	Diamondbacks
Moneyline	-104	-112
Total	o9 (-108)	u9 (-110)

All odds are correct at the time of publication and are subject to change.

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Phillies vs. Diamondbacks picks and best bets

Our model's strongest edge in today's Phillies vs. Diamondbacks matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Phillies vs. Diamondbacks game-day updates and essential details

Saturday's MLB game between the Diamondbacks and Phillies at Chase Field is scheduled to begin at 8:10PM ET.

• Who: Philadelphia Phillies vs. Arizona Diamondbacks
• Date: Saturday, September 20, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Chase Field

Dimers' full preview of Saturday's Phillies vs. Diamondbacks matchup includes our prediction, picks and the latest betting odds.

Before making any Phillies vs. Diamondbacks picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Diamondbacks, with a 51% win probability, will likely beat the Phillies on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Phillies vs. Diamondbacks insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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