Philadelphia Eagles vs. Tampa Bay Buccaneers updated prediction featuring Saquon Barkley, Bucky Irving [Week 4, 2025]

Dimers' latest NFL predictions are live for Tampa Bay Buccaneers and Philadelphia Eagles in Week 4, with our model giving the Eagles a 61% of winning against the Buccaneers on Sunday.

This update builds on our early Buccaneers-Eagles predictions, presenting renewed win probabilities, score projections, and TD predictions for Saquon Barkley, Bucky Irving, and more.

For the most accurate simulation-based insights—including spread and total picks, touchdown probabilities, and the full list of player props—head to our Eagles vs. Buccaneers page.

What's changed? Philadelphia vs. Tampa Bay updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Eagles vs. Bucs matchup stacks up. Here are the updated forecasted:

• Straight Up Win Probabilities: Eagles 61%, Buccaneers 39%
• Predicted Final Score: Eagles 24-21 Buccaneers
• Spread: Eagles (-3.5) 41%, Buccaneers (+3.5) 59%
• Total Points (43.5): Over 58%, Under 42%

As of September 25, 2025, these Eagles-Buccaneers figures reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New projections highlight the top candidates to find the end zone in Eagles-Bucs on Sunday:

Philadelphia Eagles

• Saquon Barkley: 54.0% probability
• Jalen Hurts: 53.3% probability
• A.J. Brown: 33.9% probability

Tampa Bay Buccaneers

• Bucky Irving: 47.0% probability
• Emeka Egbuka: 38.1% probability
• Sterling Shepard: 22.5% probability

Eagles vs. Bucs latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Eagles -3.5 (-105), Buccaneers +3.5 (-110)
• Moneyline: Eagles -190, Buccaneers +164
• Total: Over/Under 43.5 (-110/-105)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Eagles vs. Bucs Week 4 details

The NFL Week 4 matchup between the Buccaneers and Eagles at Raymond James Stadium is scheduled for September 28, 2025.

• Who: Philadelphia Eagles vs. Tampa Bay Buccaneers
• Date: Sunday, September 28, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Raymond James Stadium

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Conclusion

We predict the Eagles, with a 61% win probability, will likely beat the Buccaneers in Week 4 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Eagles vs. Buccaneers game, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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