Eagles vs. Buccaneers prediction: Why Philadelphia is favored to win in NFL Week 4, 2025

The Tampa Bay Buccaneers will face the Philadelphia Eagles in NFL Week 4 action at Raymond James Stadium on Sunday, starting at 1:00PM ET.

Based on updated simulation results, Dimers' proven NFL model predicts the Eagles as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Eagles-Buccaneers game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Eagles with a win probability of 61%, while the Buccaneers have 39%."

This gameday Eagles vs. Buccaneers betting preview builds on my Eagles vs. Buccaneers prediction that was published earlier in the week.

For further insights into today’s game, including the predicted score, best bets and player prop picks, visit our interactive Eagles vs. Buccaneers predictions page.

Eagles vs. Buccaneers Predictions

Since our Eagles-Buccaneers predictions earlier in the week, we have simulated the outcome of Sunday's NFL matchup between the Eagles and Buccaneers 10,000 times as part of our NFL predictions coverage.

Our independent predictive model gives the Eagles a 61% chance of beating the Buccaneers in Week 4 of the NFL season. Our predicted final score has the Eagles winning 24-21.

According to our model, the Buccaneers (+3.5) have a 59% chance of covering the spread, while the 44.5-point over/under has a 55% chance of going over.

Eagles vs. Buccaneers odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type	Eagles	Buccaneers
Spread	-3.5 (-102)	+3.5 (-110)
Moneyline	-185	+164
Total	o44.5 (-102)	u44.5 (-118)

All odds are correct at the time of publication and are subject to change.

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Eagles vs. Buccaneers picks and best bets

Our model's strongest edge in today's Eagles vs. Buccaneers matchup is on the over/under.

Our expert predictions, aligned with the current odds, reveal the best NFL picks and NFL best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Eagles vs. Buccaneers TD scorers

Who will score the first touchdown in Eagles vs. Buccaneers?

According to our model, Philadelphia's Saquon Barkley is most likely to score the first TD in Eagles vs. Buccaneers.

Our projections give Barkley a 13.5% chance of getting in for six first at Raymond James Stadium, while the Eagles running back is a 53.0% chance of registering an anytime touchdown.

First touchdown scorer predictions

Philadelphia Eagles

Player	First TD Probability
Saquon Barkley (RB)	13.5%
Jalen Hurts (QB)	13.2%
A.J. Brown (WR)	7.3%

Tampa Bay Buccaneers

Player	First TD Probability
Bucky Irving (RB)	12.0%
Emeka Egbuka (WR)	8.8%
Chris Godwin (WR)	4.6%

Anytime touchdown scorer predictions

Philadelphia Eagles

Player	Anytime TD Probability
Saquon Barkley (RB)	53.0%
Jalen Hurts (QB)	52.2%
A.J. Brown (WR)	33.5%

Tampa Bay Buccaneers

Player	Anytime TD Probability
Bucky Irving (RB)	46.8%
Emeka Egbuka (WR)	36.9%
Chris Godwin (WR)	21.3%

Eagles vs Buccaneers player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Eagles and Buccaneers. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Eagles-Buccaneers page now to access every player prop projection.

Eagles vs. Buccaneers quarterbacks

Of the starting quarterbacks, the Eagles' Jalen Hurts is projected to throw for fewer yards than the Buccaneers' Baker Mayfield.

Eagles rushing

Saquon Barkley, Jalen Hurts and Will Shipley are projected to be the leading rushers for the Eagles.

Player	Position
Saquon Barkley	RB
Jalen Hurts	QB
Will Shipley	RB

Buccaneers rushing

Bucky Irving, Baker Mayfield and Rachaad White are expected to lead the Buccaneers in rushing yards.

Player	Position
Bucky Irving	RB
Baker Mayfield	QB
Rachaad White	RB

Eagles receiving

A.J. Brown, DeVonta Smith, Dallas Goedert, Saquon Barkley and Jahan Dotson are projected to top the receiving yards for the Eagles.

Player	Position
A.J. Brown	WR
DeVonta Smith	WR
Dallas Goedert	TE
Saquon Barkley	RB
Jahan Dotson	WR

Buccaneers receiving

Emeka Egbuka, Chris Godwin, Sterling Shepard, Cade Otton and Bucky Irving are projected to lead the Buccaneers in receiving yards.

Player	Position
Emeka Egbuka	WR
Chris Godwin	WR
Sterling Shepard	WR
Cade Otton	TE
Bucky Irving	RB

Eagles vs. Bucs game-day updates and essential details

The NFL Week 4 matchup between the Buccaneers and Eagles at Raymond James Stadium is scheduled to begin at 1:00PM ET.

• Who: Philadelphia Eagles vs. Tampa Bay Buccaneers
• Date: Sunday, September 28, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Raymond James Stadium

Dimers' full preview of Sunday's Eagles vs. Buccaneers matchup includes our prediction, picks and the latest betting odds.

Before making any Eagles vs. Bucs picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Eagles, with a 61% win probability, will likely beat the Buccaneers in Week 4 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Eagles vs. Buccaneers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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