Novak Djokovic vs. Taylor Fritz prediction, odds, picks for US Open 2025

Novak Djokovic and Taylor Fritz will lock horns in the quarterfinals of the US Open 2025 on Tuesday.

Based on updated simulation results, Dimers' advanced tennis model projects Novak Djokovic as the most likely winner of the match.

For expanded analysis of Tuesday's match, including best bets and picks, visit our interactive Djokovic vs. Fritz predictions page.

Djokovic vs. Fritz prediction: Who will win and advance to the semifinals?

Using trusted machine learning and data, we have simulated the outcome of Tuesday's Djokovic-Fritz men's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model currently gives Djokovic a 68% chance of defeating Fritz in the US Open 2025.

Additionally, Djokovic has a 64% chance of winning the first set, while the under 40.5 games has a 60% chance of hitting, according to our model.

For more insights into the growing popularity of betting on the sport, check out our comprehensive analysis of tennis' rise in the U.S. sports betting market.

Novak Djokovic vs. Taylor Fritz odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Djokovic	Fritz
Moneyline	-220	+180
First Set	-175	+137
Total Games	o40.5 (-105)	u40.5 (-115)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Djokovic vs. Fritz picks and best bets

Our model's biggest edge in today's Djokovic vs. Fritz match is on the first set.

Our expert predictions, aligned with the current odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Djokovic vs. Fritz updates and essential details

The US Open 2025 match between Novak Djokovic and Taylor Fritz is scheduled to begin on Tuesday at 8:10PM ET.

• Who: Novak Djokovic vs. Taylor Fritz
• Date: Tuesday, September 2, 2025
• Approx. Time: 8:10PM ET/5:10PM PT
• Tournament: US Open Men's Singles 2025
• Round: Quarterfinals

All dates and times in this article are United States Eastern Time unless otherwise stated.

Dimers.com's full preview of Tuesday's Djokovic vs. Fritz match includes our prediction, picks and the latest betting odds.

Before making any Novak Djokovic vs. Taylor Fritz picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
• Stay informed with guides on where online sports betting is currently legal and which states could legalize next
• Improve your chances with proven sports betting strategies that apply to tennis and more

Conclusion

We predict Novak Djokovic, with a 68% win probability, will likely beat Taylor Fritz at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Djokovic vs. Fritz insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on Tennis

Stay up-to-date with the latest tennis news and parlay picks throughout the year. Plus, Dimers' ATP and WTA world rankings showcase our in-house approach to accurately ranking every men's and women's player in the world.