Novak Djokovic vs. Jan-Lennard Struff prediction, odds, picks for US Open 2025

Novak Djokovic and Jan-Lennard Struff will meet in the fourth round of the US Open 2025 on Sunday.

Based on the latest simulations, Dimers' proven tennis model predicts Novak Djokovic as the most likely winner of the match.

"Using the most recent data, we ran 10,000 simulations of Sunday's Djokovic-Struff match," said Dimers data analyst Greg Butyn.

"After accounting for recent updates and other variables, our prediction shows Novak Djokovic with a win probability of 88%, while Jan-Lennard Struff has 12%."

For expanded analysis of Sunday's match, including best bets and picks, visit our interactive Djokovic vs. Struff predictions page.

Djokovic vs. Struff prediction: Who will win and advance to the Quarterfinals?

Using trusted machine learning and data, we have simulated the outcome of Sunday's Djokovic-Struff men's singles match 10,000 times as part of our tennis predictions coverage.

Our independent predictive model currently gives Djokovic an 88% chance of beating Struff in the US Open 2025.

Additionally, Djokovic has an 80% chance of winning the first set, while the under 36.5 games has a 61% chance of hitting, according to our model.

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Novak Djokovic vs. Jan-Lennard Struff odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Djokovic	Struff
Moneyline	-599	+490
First Set	-333	+250
Total Games	o36.5 (-110)	u36.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Djokovic vs. Struff picks and best bets

Our model's strongest edge in today's Djokovic vs. Struff match is on the first set.

Our expert predictions, matched against the latest odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Djokovic vs. Struff updates and essential details

The US Open 2025 match between Novak Djokovic and Jan-Lennard Struff is scheduled to commence on Sunday at 7:00PM ET.

• Who: Novak Djokovic vs. Jan-Lennard Struff
• Date: Sunday, August 31, 2025
• Approx. Time: 7:00PM ET/4:00PM PT
• Tournament: US Open Men's Singles 2025
• Round: Fourth round

All dates and times in this article are United States Eastern Time unless otherwise stated.

Dimers.com's comprehensive preview of Sunday's Djokovic vs. Struff match includes our prediction, picks and the latest betting odds.

Before making any Novak Djokovic vs. Jan-Lennard Struff picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
• Stay informed with guides on where online sports betting is currently legal and which states could legalize next
• Improve your chances with proven sports betting strategies that apply to tennis and more

Conclusion

We predict Novak Djokovic, with an 88% win probability, will likely beat Jan-Lennard Struff at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Djokovic vs. Struff insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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