North Alabama vs. Southeast Missouri State prediction: Southeast Missouri State favored to win in college football Week 2, 2025

Southeast Missouri State and North Alabama will meet in Week 2 college football action at Houck Field on Saturday, commencing at 7:00PM ET.

Based on updated simulations, Dimers' advanced college football model predicts Southeast Missouri State as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive North Alabama vs. Southeast Missouri State predictions page.

North Alabama vs. Southeast Missouri State prediction: Who will win, cover the spread?

Using powerful machine learning and data analysis, we have simulated the result of North Alabama vs. Southeast Missouri State 10,000 times as part of our college football predictions coverage.

Our leading predictive model currently gives Southeast Missouri State an 83% chance of defeating North Alabama. Our predicted final score has Southeast Missouri State winning 36-20.

According to our model, North Alabama (+16.5) has a 51% chance of covering the spread, while the over/under total of 55.5 points has a 52% chance of staying under.

North Alabama vs. Southeast Missouri State odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	North Alabama	Southeast Missouri State
Spread	+16.5 (-110)	-16.5 (-110)
Moneyline	+500	-650
Total	o55.5 (-110)	u55.5 (-110)

All odds are correct at the time of publication and are subject to change.

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North Alabama vs. Southeast Missouri State picks and best bets

Our model's strongest edge in today's North Alabama vs. Southeast Missouri State matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

North Alabama vs. Southeast Missouri State game-day updates and essential details

Saturday's college football matchup between Southeast Missouri State and North Alabama at Houck Field is scheduled to begin at 7:00PM ET.

• Who: North Alabama vs. Southeast Missouri State
• Date: Saturday, September 6, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Houck Field

Dimers.com's full preview of Saturday's North Alabama vs. Southeast Missouri State matchup includes our prediction, picks and the latest betting odds.

Before making any North Alabama vs. Southeast Missouri State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Southeast Missouri State, with an 83% win probability, will likely beat North Alabama on Saturday.

AI and automation have enhanced this article to quickly deliver accurate North Alabama vs. Southeast Missouri State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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