North Alabama vs. Illinois State prediction: Why Illinois State is favored to win in college football Week 4, 2025

Illinois State and North Alabama will clash in Week 4 college football action at Hancock Stadium on Saturday, beginning at 1:00PM ET.

Based on updated simulation results, Dimers' advanced college football model projects Illinois State as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive North Alabama vs. Illinois State predictions page.

North Alabama vs. Illinois State prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the result of North Alabama vs. Illinois State 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Illinois State an 85% chance of defeating North Alabama. Our predicted final score has Illinois State winning 36-19.

According to our model, North Alabama (+17.5) has a 54% chance of covering the spread, while the 57.5-point over/under has a 53% chance of going over.

North Alabama vs. Illinois State odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	North Alabama	Illinois State
Spread	+17.5 (-118)	-17.5 (-104)
Moneyline	+650	-800
Total	o57.5 (-110)	u57.5 (-110)

All odds are correct at the time of publication and are subject to change.

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North Alabama vs. Illinois State picks and best bets

Our model's biggest edge in today's North Alabama vs. Illinois State matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

North Alabama vs. Illinois State game-day updates and essential details

Saturday's college football matchup between Illinois State and North Alabama at Hancock Stadium is scheduled to start at 1:00PM ET.

• Who: North Alabama vs. Illinois State
• Date: Saturday, September 20, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Hancock Stadium

Dimers' comprehensive preview of Saturday's North Alabama vs. Illinois State matchup includes our prediction, picks and the latest betting odds.

Before making any North Alabama vs. Illinois State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Illinois State, with an 85% win probability, will likely beat North Alabama on Saturday.

AI and automation have enhanced this article to quickly deliver accurate North Alabama vs. Illinois State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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