Week 4 NFL Parlay Picks: Improved +1337 Betting Odds Available Today

Week 4 of the NFL season is here, and we're zeroing in on one of the most exciting and profitable markets in sports betting: quarterback rushing NFL props. Mobile quarterbacks are the new gold standard in the league, and their rushing lines offer a great way to build a high-payout NFL parlay.

This Sunday, we’ve found five must-hit QB rushing lines at DraftKings Sportsbook that combine for some juicy NFL odds. By packaging these five players to each register 25+ rushing yards, we unlock a five-leg NFL parlay at +1337 odds.

That means a simple $10 NFL parlay wager will pay out a handsome $143.70 if all five dual-threat stars scramble their way to success on Sunday!

Let’s break down the Sunday parlay picks, all sourced from the Dimers Pro Player Projections hub.

Dimers Pro subscribers get unlimited access to the NFL player projection for less than $1 per day.

NFL Parlay Sunday

1. Josh Allen 25+ Rushing Yards

• Matchup: Saints vs. Bills at Highmark Stadium (1PM)
• Date: Sunday, September 28, 2025
• Projection: 26.8 Rushing Yards
• Odds: -128

The Bills are heavy favorites, which often means running the ball to kill the clock. However, Josh Allen’s rushing production is matchup-independent, driven by his sheer athleticism and tendency to extend plays. Against the Saints, who will likely be trying to blitz to pressure Allen, he has a strong chance to scramble for multiple 10+ yard gains. The Dimers Pro player projection of 26.8 yards is right on the line, but Allen’s history as a runner makes this a comfortable "Over" to start our parlay.

RELATED: Full betting predictions for Saints vs. Bills

2. Jalen Hurts 25+ Rushing Yards

• Matchup: Eagles vs. Buccaneers at Raymond James Stadium (1PM) 
• Date: Sunday, September 28, 2025
  
• Projection: 41.8 Rushing Yards
• Odds: -316

This is the cornerstone of our parlay. Jalen Hurts is a running back playing quarterback, and his high projection (41.8 yards) and short odds reflect the near-certainty of him hitting this mark. Whether it's on designed QB sneaks, zone-read options, or escaping pressure, Hurts is one of the most reliable sources of rushing yardage in the league. You have to swallow the heavy juice (-316), but it significantly increases the overall probability of our NFL parlay hitting.

RELATED: Full betting predictions for Eagles vs. Bucs

3. Daniel Jones 25+ Rushing Yards

• Matchup: Colts vs. Rams at SoFi Stadium (4.05PM)
• Date: Sunday, September 28, 2025
• Projection: 25.3 Rushing Yards
• Odds: -108

The new offensive system in Indianapolis under Shane Steichen has unlocked Daniel Jones's mobility as a key component of the attack. While his projection of 25.3 yards is the slimmest on our list, the near even-money NFL odds (-108) offer fantastic value for a player who has consistently demonstrated an ability to beat the 25-yard mark. Against a potentially disruptive Rams pass rush, Jones will need to use his legs to keep drives alive, securing his leg of the parlay.

RELATED: Full betting predictions for Colts vs. Rams

4. Caleb Williams 25+ Rushing Yards

• Matchup: Bears vs. Raiders at Allegiant Stadium (4.25PM)
• Date: Sunday, September 28, 2025
• Projection: 30.1 Rushing Yards
• Odds: -129

The electric youngster, Caleb Williams, is a dynamic player who's still learning to navigate the pocket, which often leads to meaningful scrambles. His mobility is a crucial weapon for a rejuvenated Bears offense. The Raiders' defense will be a formidable test, but Williams's calculated running, combined with inevitable broken plays, should push him past the 25-yard mark. A 30.1-yard projection at -129 odds is a strong indication of value for this key NFL prop.

RELATED: Full betting predictions for Bears vs. Raiders

5. Patrick Mahomes 25+ Rushing Yards

• Matchup: Ravens vs. Chiefs at Arrowhead Stadium (4.25PM)
• Date: Sunday, September 28, 2025
• Projection: 28.7 Rushing Yards
• Odds: -128

Don't let the arm talent fool you - Patrick Mahomes is a highly effective runner when the situation demands it. Facing the Ravens' fierce defense, which thrives on man coverage and pressure, Mahomes will have to rely on his scrambling ability more than usual. When his primary receivers are covered downfield, Mahomes often picks up critical first downs with his legs. The 28.7-yard projection suggests the books know this will be a scrappy game where Mahomes' legs are vital. This leg brings our NFL Parlay home at good enough odds.

RELATED: Full betting predictions for Ravens vs. Chiefs

NFL Parlay Week 4

DraftKings Odds: +1337

Payout: $143.70 ($10 stake)

Lock in this five-leg NFL parlay for Sunday's slate and watch these quarterbacks try and scramble their way to a nice payout and, hopefully, some Week 4 touchdowns!