NFL best bets today: Week 4 MNF picks include Jets vs. Dolphins play [9/29/2025]

Today’s NFL picks for September 29, 2025 are here, with Monday’s NFL best bets built on tens of thousands of predictive simulations analyzing the latest odds and matchups.

These NFL best bets include matchups like Jets vs. Dolphins and Bengals vs. Broncos, with this article updated throughout the day to feature the highest-probability plays based on thousands of data-driven simulations from our predictive analytics model.

But if you're serious about long-term profit, it's not just about probability—it's about edge. To unlock our highest-edge NFL bets—the ones with true long-term value—join Dimers Pro.

Pro members get unlimited access to everything Dimers has to offer on Monday, September 29, 2025, including our full set of picks and best bets for today and the week ahead.

List of NFL best bets tonight [9/29, updated 9:11AM ET]

After digging deep into the numbers and running thousands of simulations, our famous predictive analytics model has identified the best football bets for Monday, September 29, 2025.

Jets vs. Dolphins under 45.5 points (-115)

• Probability: 58.5%
• Edge: 5.1%
• Matchup: Jets vs. Dolphins (7:15PM ET, Monday)

Our model has pinpointed a high-probability NFL betting opportunity tonight, which comes in the Jets vs. Dolphins game. We recommend an over/under bet on under 45.5 points at -115 odds, with our analysis showing a 58.5% chance of hitting and a compelling edge of 5.1%.

Bengals +7.5 (-108)

• Probability: 55.8%
• Edge: 3.9%
• Matchup: Bengals vs. Broncos (8:15PM ET, Monday)

Our model has found another strong NFL bet for Monday's sports action, this time in the matchup between the Bengals and Broncos. We suggest placing a spread wager on Bengals +7.5 at -108 odds, with a 55.8% probability delivering a 3.9% edge.

Bengals ML (+380)

• Probability: 25.7%
• Edge: 4.8%
• Matchup: Bengals vs. Broncos (8:15PM ET, Monday)

Our model has found another strong NFL bet for Monday's football action, also in the Bengals vs. Broncos game. We recommend a bet on Bengals ML at +380 odds. Our projections shows a 25.7% probability and 4.8% edge for this wager.

NFL best bets: Monday, 9/29/2025

As of 9:11AM ET, here are our top three NFL bets by probability recommended by our model:

Matchup	Bet	Odds	Probability	Edge
Jets vs. Dolphins	Under 45.5 Points	-115 @ DraftKings	58.5%	5.1%
Bengals vs. Broncos	Bengals +7.5	-108 @ FanDuel	55.8%	3.9%
Bengals vs. Broncos	Bengals ML	+380 @ DraftKings	25.7%	4.8%

Dimers Pro unlocks instant access to the most valuable bets across all sports, powered by our advanced predictive model.

Today, Dimers Pro subscribers have access to three NFL picks—with access to all of these being what makes a difference over time.

Join Dimers Pro now to access these picks, as well as a comprehensive range of props, trends and parlays for September 29, 2025.

List of upcoming NFL games to bet on [9/29/2025]

• Jets vs. Dolphins (7:15PM ET, Monday)
• Bengals vs. Broncos (8:15PM ET, Monday)

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More about NFL

The bets on this page form part of our NFL player props and NFL best bets series.

For more NFL betting content, we have NFL trends for every game, as well as daily NFL betting news and the latest Super Bowl odds and predictions.

Conclusion

Our NFL best bets are locked and loaded for September 29, 2025, featuring plays such as under 45.5 points in the Jets vs. Dolphins matchup and Bengals +7.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate NFL insights quickly, with human oversight ensuring high editorial quality. Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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