NFL 2020 Philadelphia Eagles vs. San Francisco 49ers: Predictions, picks and bets

‍Predictions based on 10,000+ simulations

The 49ers absolutely dismantled the injury-ravaged Giants last week as they look to stay in touch with a hotly contested NFC West, whilst the Eagles played out a 23-23 draw with the Bengals to remain winless.

As you'll see in our NFL Bet Hub predictions below, we’ve got the 49ers grabbing another win on Sunday evening.

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💪 Spread

The Niners are 8 point favorites for this matchup as they aim for their third straight win. They covered with ease against the Giants last week but may find it tougher against Philly.

🚀 Over/Under

A low total has been set by the books for this one, and our predicted score has remained in line with this all week. Below is what our computer believes to be the best O/U play you can make based on the latest team news and shifts in the betting market.

💵 Moneyline

The 49ers are the stronger team in this matchup and will feel good about their chances. In saying that, our model is continually crunching the numbers to find the best value at the ML, so at long odds the Eagles may be the play.

🏈 Dimers' take-out

The 49ers need to keep winning to keep up with their division rivals but the Eagles should put in a shift as well. If you’re keen for some action, check out the best NFL promos for this week, here.

Read our comprehensive online sportsbook reviews here.

*Odds and probabilities correct at time of publishing.