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Penrith Panthers vs. Newcastle Knights Prediction: Panthers Predicted to Win Saturday's NRL Round 12 Matchup [5/24/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Our expert prediction for Saturday's Penrith Panthers vs Newcastle Knights matchup.
The Penrith Panthers and Newcastle Knights are scheduled to meet in the National Rugby League (NRL) at Panthers Stadium on Saturday, starting at 3:30AM ET.
Based on the latest simulations, Dimers' proven NRL model (see Dimers Pro for full access) predicts the Panthers as the most likely winner of today's game.
"Our team has used the latest data to run 10,000 simulations of Saturday's Knights-Panthers game," said Pat Sharyon from Dimers.
"By incorporating recent updates and various other inputs, we estimate that the Panthers are more likely to win, while the Knights have a lower chance of victory."
For further insights into Saturday's matchup, including best bets and picks, visit our interactive Knights vs. Panthers predictions page.
Panthers vs. Knights Prediction: Who Will Win Round 12 Game?
Using powerful machine learning and data, we have simulated the outcome of Saturday's NRL matchup between the Knights and Panthers 10,000 times as part of our NRL predictions coverage.
Our famous predictive model currently gives the Panthers a 72% chance of beating the Knights.
According to our model, the Panthers (-4.5) have a 59% chance of covering the spread, while the over/under total of 42.5 has a 53% chance of going over.
Knights vs. Panthers Odds
We have sourced the best NRL odds in America for this game, which are listed here:
| Bet Type | Knights | Panthers |
|---|---|---|
| H2H (Moneyline) | +148 | -185 |
| Line (Spread) | +4.5 (-120) | -4.5 (-110) |
| Total | o42.5 (-112) | u42.5 (-112) |
All odds are correct at the time of publication and are subject to change.
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Panthers vs. Knights Game-Day Updates and Essential Details
Saturday's Australian rugby league action between the Panthers and Knights at Panthers Stadium is scheduled to begin at 3:30AM ET.
- Who: Newcastle Knights vs. Penrith Panthers
- Date: Saturday, May 24, 2025
- Time: 3:30AM ET/12:30AM PT
- Venue: Panthers Stadium
The NRL is available to bet on in the US through all major sportsbooks, with there even being games played in Vegas each season as of 2024.
Dimers.com's in-depth preview of Saturday's Knights vs. Panthers matchup includes our prediction, picks and the latest betting odds.
Before making any Knights vs. Panthers picks, be sure to check out the latest NRL predictions and betting advice from Dimers Pro.
Conclusion
We predict the Panthers, with a 72% win probability, will likely beat the Knights on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Knights vs. Panthers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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